How the rival formulations are lining up
Team Oxford Vaccine Group Captain Sarah Gilbert, Prof of Vaccinology, University of Oxford Game plan Non-replicating Viral Vector. Uses chimpanzee cold virus to deliver gene for the coronavirus spike protein to human cells Results “Acceptable safety profile”. Antibody response after two doses and produces T cells. Results due in October. Deals for 2billion doses. Issues Likely to prevent severe disease rather than protect entirely. Not clear how long protection lasts.
Team Biontech Captain Ugur Sahin, Prof of Experimental Oncology, Mainz University Game Plan Messenger RNA, synthetic genetic material instructs body to make its own copy of virus protein to spark immune response Results “Acceptable safety profile”. Antibody and T-cell response within 14 days. First results due by October. Deals secured for 630million doses. Issues Requires two doses; full effectiveness remains unclear; not clear how long protection will last.