The Daily Telegraph

How the rival formulatio­ns are lining up

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Team Oxford Vaccine Group Captain Sarah Gilbert, Prof of Vaccinolog­y, University of Oxford Game plan Non-replicatin­g Viral Vector. Uses chimpanzee cold virus to deliver gene for the coronaviru­s spike protein to human cells Results “Acceptable safety profile”. Antibody response after two doses and produces T cells. Results due in October. Deals for 2billion doses. Issues Likely to prevent severe disease rather than protect entirely. Not clear how long protection lasts.

Team Biontech Captain Ugur Sahin, Prof of Experiment­al Oncology, Mainz University Game Plan Messenger RNA, synthetic genetic material instructs body to make its own copy of virus protein to spark immune response Results “Acceptable safety profile”. Antibody and T-cell response within 14 days. First results due by October. Deals secured for 630million doses. Issues Requires two doses; full effectiven­ess remains unclear; not clear how long protection will last.

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