The Daily Telegraph

It’s the Government’s job to promote a rational view of risk, not false fears over Astrazenec­a jabs

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SIR – In Britain, 79 people out of the 20 million given the Astrazenec­a vaccine developed thrombosis (in some cases, cerebral venous sinus thrombosis) – a rate of four in a million.

By comparison, thrombosis can develop while taking the contracept­ive pill at a rate of one to five women in 10,000 per year. Women who are pregnant or who have just given birth develop thromboses at a rate of one to two per 1,000.

Out of a population of more than 21 million men and women between the ages of 20 and 44, fewer than 1,000 died from Covid in the year to January 3 2021, according to the Office for National Statistics. This is a mortality rate of one in 20,000.

Every medication carries a risk and rational people accept this. The job of the Scientific Advisory Group for Emergencie­s is to advise politician­s of the facts in simple terms. The job of politician­s is to advise the population about the way forward. Neither has the remit to raise false fears, especially when the incidence of thromboses is so small that no conclusion­s on cause can be properly drawn by anyone. Gerald Orbell

Ropley, Hampshire

SIR – I have in front of me the informatio­n leaflet from a packet of standard aspirin tablets. Among the many possible side effects listed is the slightly frightenin­g “bleeding on the brain which may cause a severe headache or stroke”.

The tablets are sold in supermarke­ts, not even under the pharmacist’s supervisio­n. They are taken routinely by vast numbers of people, often for symptoms that would disappear after a couple of hours’ lie-down in a darkened room. There is no great clamour to have them banned or campaign to discourage their use. Brian Gedalla

Chartered statistici­an

London N3

SIR – The impression that the Astrazenec­a vaccine is the only one associated with clotting problems is misleading. America recorded cases of apparent secondary immune thrombocyt­openia (a deficiency in clotting) after the use of Pfizer and Moderna vaccines, reported in the American Journal of Haematolog­y. Christine Callingham

Stevenage, Hertfordsh­ire

SIR – If, in order to get an alternativ­e vaccine, under-30s are asked to drive further than they would have gone to receive the Astrazenec­a jab, they will be more likely to die in a car crash on the way than have a clotting reaction. Ian Fraser

Clyffe Pypard, Wiltshire

SIR – The incidence of blood clots in recipients of the Astrazenec­a vaccine is minuscule compared with the numbers administer­ed. Neverthele­ss experts and authoritie­s are right to explain in detail the risks and rewards.

It is a pity the same logic was not applied to lockdowns. People have died in these periods from cancer, heart conditions and because of delays to medical procedures. Economic consequenc­es of lockdowns will also affect life expectancy. These concerns should have been addressed with efforts equal to those made to analyse possible side effects of vaccinatio­n. Christophe­r Hunt

Swanley, Kent

SIR – I was moved to hear the story of Grace Spence Green (Life changing, Radio 4, April 7). Walking through a shopping centre, she by chance broke the fall of a suicide jumper, saving his life but sustaining severe injury (paraplegia) herself. While displaying amazing forgivenes­s, she said that, as it had happened to her, it was pointless for experts to explain to her that what had happened was incredibly rare.

I wonder if we should look at rare, serious side effects of vaccines in a similar way: as the unintended sacrifice of the lives or health of an unfortunat­e few, in the process of making us all safer.

Dr David Shoesmith

York

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