The Daily Telegraph

Herd immunity may be coming closer as vaccine takes the strain

- By Sarah Knapton SCIENCE EDITOR

‘Assuming nothing truly left field happens, this pandemic is pretty much over for the UK’

On July 7, a group of 122 scientists and doctors wrote a letter in The Lancet calling for Freedom Day to be delayed, accusing the Government of embarking on a “dangerous and unethical experiment”.

They warned that herd immunity would not be reached in time to prevent hundreds of thousands of new infections, and called for restrictio­ns and mask-wearing to remain indefinite­ly.

A day later, a senior official at the World Health Organisati­on (WHO) accused the UK of “moral emptiness and epidemiolo­gical stupidity” in pressing on with reopening on July 19.

However, far from a soaring wave of infections that could pass 200,000 a day, it looks like Britain peaked at around 60,000 cases on July 15.

Although cases rose for the first time in seven days on Wednesday, infections have fallen by 36 per cent in a week. Scientists say they are “puzzled” by the recent drop, blaming it on the heatwave, school closures, the end of the Euros football tournament, or a decline in testing.

It may even be the case that the pingdemic is causing mass isolation and lowering transmissi­on or else people are no longer being tested for fear of missing planned holidays, they say. Few straws have been left unclutched in the bid to explain the anomaly. Yet amid the bewilderme­nt, few seem willing to consider the prospect that it is the vaccinatio­n programme which is doing most of the heavy lifting.

Britain may be finally nearing the holy grail of herd immunity.

Latest Office for National Statistics figures suggest that nearly 92 per cent of adults now carry antibodies to coronaviru­s, representi­ng about 73 per cent of the population as a whole, and we now know that some people are naturally immune to the virus.

University College London (UCL) estimates total population immunity is now at 87 per cent, although they believe the Delta variant has shifted the immunity threshold to 93 per cent – meaning we’re not quite there yet.

With a new mutating virus, the threshold can move significan­tly as the disease becomes more infectious.

But being close to the threshold makes it harder for the virus to transmit, even if it does not stop it entirely.

Dr David Matthews, from the University of Bristol, said: “In terms of herd immunity – by which we mean the virus has managed to reach everybody and therefore most people will have a level of immune memory – I suspect we’re very close to it.

“Assuming nothing truly spectacula­rly left field happens then this pandemic is pretty much over for the UK. I suspect we will not see a major surge this winter, or any serious levels of fatalities.

“The more we close the gap on the last 10 per cent who haven’t had the vaccine the better we will be. Everyone will eventually meet the virus and it is far better to do so vaccinated.” As early as July 7, Dr Meaghan Kall of Public Health England said the antibody data suggested the over-24s age group were “very close to herd immunity”.

And, paradoxica­lly, mass mixing in the Euros may also have helped push the country towards nationwide protection.

Prof Paul Hunter of the University of East Anglia, said: “A lot of people might be disgusted by me saying this, but ultimately the Euros might turn out to be one of the things that make the rest of the summer less stressful, as we’ve effectivel­y immunised a lot more younger people who wouldn’t otherwise have come for or been available for a vaccine.

“But I would stress that I would never suggest that as a control strategy in advance.”

Prof Karl Friston, of University College London, who believed that Britain reached herd immunity in the spring, only to lose it again with the emergence of the Delta variant, said we were once again close to reaching the threshold.

“We are currently close to – but not at – herd immunity, according to real-time estimates based upon dynamic causal modelling,” he said.

“But as witnessed by the recent decline in notificati­on rates, we do not need to reach a herd immunity threshold to bring the effective R-number below one and, in principle, suppress viral transmissi­on.”

As always, there are caveats. The disparate nature of the epidemic means some areas could already be at herd immunity levels while others may never get there, based on localised vaccinatio­n uptake and demographi­cs.

But it does seem that enough people are now protected that the virus is running out of steam.

We are finally reaching a point where the virus is endemic, our older population is protected, and youngsters can catch the virus safely at a time in their lives when their immune system is waiting to be primed by new diseases.

Dr Matthews added: “I’ve worked on a lot of respirator­y viruses and controvers­ially I believe this virus isn’t a killer. Flu kills babies and old people and it’s quite capable of killing people who have had the vaccine, but the issue here is that collective­ly as a species humans have no memory of this virus, so everyone’s immune system is starting from scratch.

“That’s OK if you’re a child but not if you’re in your 50s, 60s and 70s and relying on the memory of previous viruses. I think we will eventually live in a world where you will meet this virus as a kid and develop immunity early. Reaching a truce with the virus is probably where we’re heading.”

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