The Daily Telegraph

Gender inequality ‘shrinks women’s brains’ by causing chronic stress

Difference in grey matter is greater in countries where females have fewer rights, researcher­s find

- By Sarah Knapton Science editor

GENDER inequality may shrink women’s brains, research has suggested.

A study by the University of Oxford that looked at scans of more than 7,800 people aged 18 to 40 found significan­t brain thinning in women living in countries with fewer female rights and maledomina­ted cultural norms.

In countries where there was greater gender inequality, such as India, Turkey and Brazil, the thickness of the grey matter in the right hemisphere of women’s brains was up to 5 per cent thinner than men’s.

However, in Scandinavi­an countries such as Sweden and Finland, there was no significan­t difference between the sexes, with women showing thicker grey matter than men in some areas.

In Britain, researcher­s found about 0.5 per cent thinning in the right hemisphere of female brains, which they say could be a result of gender inequality.

The areas of the brain affected – the anterior cingulate cortex and orbitofron­tal cortex – are linked to stress and emotions. Researcher­s believe that living in unequal environmen­ts may cause chronic stress that damages the connection­s between brain cells and shrinks the grey matter. Lack of opportunit­ies in school or at work may also prevent the developmen­t of brain connection­s, the researcher­s suggested.

Experts said the level of brain thinning was similar to that seen in people with conditions such as schizophre­nia.

Dr Nicolas Crossley, the lead author, who is a visiting professor in the department of psychiatry at the University of Oxford and an associate professor at the Pontificia Universida­d Católica in Chile, said: “Our analysis suggests some sex difference­s in brain structure are associated with the adverse social environmen­t under which many women live.

“These changes were particular­ly located in regions involved in control of emotions and that are also affected in stress-related disorders such as depression and post-traumatic stress disorder.

“We therefore think that what we are seeing is the effect of chronic stress in women’s brains in gender unequal environmen­ts. Stress affects neurons’ connection­s, which we would then see as thinning of the grey matter cortex in MRI studies.

“However, other mechanisms could also be involved, such as the effect of reduced opportunit­ies including education in women’s brains, leading to lower developmen­t of connection­s.”

The study was published in the journal Proceeding­s of the National Academy of Sciences in collaborat­ion with more than 70 other institutio­ns.

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