The Guardian

Pick your favourite jab? In most of the world choice isn’t an option

- Sarah Boseley

Until now, almost nobody in the UK has been able to choose which Covid vaccine they were given – even, apparently, cheerleade­rs for the home-grown Oxford-AstraZenec­a jab such as Boris Johnson and the NHS boss, Simon Stevens, who received it very publicly in an effort to boost confidence earlier this year.

But now, all adults under 30 are to be offered an alternativ­e to the AstraZenec­a jab and the effect of that may be to undo some of Johnson and Stevens’ work. That age group – as long as they are fit and healthy – run very little risk from Covid. The reasoning is that they could possibly run a greater risk from the very rare side-effects of the jab, which are blood clots allied to low platelets. That’s not because they are more likely to get blood clots – just less likely to end up in hospital from Covid.

The blood clots causing concern are very rare, affecting four in a million people who have had the vaccine in the UK. Of 79 people who have suffered them, 19 have died, and only three of these were aged under 30. But for people over 30, the risks of Covid rise. And there is no doubt that the AstraZenec­a vaccine saves lives – 6,000 so far in the UK, according to the Medicines and Healthcare products Regulatory Authority (MHRA), which approved it.

It’s not the MHRA which has said young adults should have the choice of an alternativ­e. Both the UK regulator and its EU equivalent, the European Medicines Agency, say the vaccine is safe and effective, the side-effects are rare and people should carry on having it. It is the Joint Committee on Vaccines and Immunisati­on, an independen­t body of scientists which advises the government, that has recommende­d giving the under-30s another option.

So far, people in the UK have gratefully accepted whichever vaccine they are offered. You are not told until you arrive at the vaccinatio­n centre which one it will be. The actual difference­s in efficacy between the AstraZenec­a and Pfizer jabs are slight – the variation has as much to do with technicali­ties such as the definition of illness in the trials.

But it’s easy to imagine that people’s readiness to have what they are given may change. The “course correction”, as England’s deputy chief medical officer, Prof Jonathan Van-Tam, calls it, may be slight but it will probably have a disproport­ionate impact on confidence – not just in the UK, where there are other vaccine options, but in parts of the world where there are not, and where the affordable and easy-to-use AstraZenec­a vaccine is the only life-saver available.

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