The Herald

It may seem like deja vu... but what happens in weeks ahead is still far from certain

- By Helen Mcardle

IT IS almost a year to the day since the UK’S Covid vaccinatio­n drive launched on December 8 when Margaret Keenan, a 90-year-old in Coventry, became the first person in the world to be immunised outside of a clinical trial.

Within weeks it became clear that a highly transmissi­ble new variant, later dubbed Alpha, which had spread from Kent, would slow the return to normality and cause thousands of extra Covid deaths during a devastatin­g winter wave.

Twelve months later, many scientists believed the virus had evolved into its “peak” form with the subsequent rise of Delta, a strain that crushed all others wherever it took hold.

Now, having amassed half a Greek alphabet of variants already, the world is faced with a new unknown: Omicron.

Like the first “variant of concern” Alpha, it shares a marker – the S-gene dropout – which enables potential cases to be detected quickly in PCR testing before being confirmed through genomic sequencing.

Surveillan­ce indicates that these “S-drop” cases began rising from November 16, though not all were Omicron. Those that are, are concentrat­ed in Lanarkshir­e and Greater Glasgow and Clyde.

Could COP26 have seeded the new variant into the west of Scotland? The first known case of Omicron was detected in Botswana in a specimen collected on November 9 – three days before the summit ended – but the variant had almost certainly been spreading in Africa for weeks.

So far, contact tracing has found no link. However, there is evidence of community transmissi­on – described as “limited” at this stage – since at least some of Scotland’s confirmed cases cannot be traced to travel.

For now, government­s at Holyrood and Westminste­r are steering clear of the curfews, hospitalit­y closures and circuit breakers that characteri­sed the battle with Alpha.

Vaccines may not have put an end to Covid as we wished, but immunity is still much higher than it was and boosters – not lockdown – will be the first line of defence, bolstered by surveillan­ce and sequencing to find cases, tougher rules on travel (hotel quarantine for red-list countries and PCR testing for all arrivals) and 10 days of self-isolation for anyone identified as a close contact of someone infected with Omicron – even if fully vaccinated.

Whether this will be enough depends on a lot of unknowns: its transmissi­bility; whether and how well it can escape vaccines; whether it causes more severe disease; and to what extent Omicron has already spread in the UK.

It also depends on us: is the public willing to “step up” compliance, or has apathy set in? Whatever the answers, we will probably know them by Christmas.

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