The House

The localised impact of Respirator­y Syncytial Virus (RSV) on infants, families and the NHS

Rebecca Catterick General Manager, Sanofi Vaccines UK and Ireland

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RSV is a respirator­y virus that impacts nearly all infants by the age of two.1 While in most cases the virus is mild,2 it can also lead to more severe complicati­ons as the leading cause of bronchioli­tis in infants.3

The Royal College of Physicians has stated how the cost-of-living crisis could negatively impact population health in the 2022-23 winter season, with access to heating, healthier foods and travel to medical appointmen­ts restricted.4 Combined with the expected surge in respirator­y virus transmissi­ons this winter,5 NHS services may be under pressure to provide the necessary support infants and families impacted by RSV require.

At Sanofi, we recognise the impact that COVID-19 has had on the NHS and the additional difficulty of managing forthcomin­g winter seasons as COVID-19 potentiall­y co-circulates with flu, RSV and other respirator­y viruses.6 Using Hospital Episode Statistics data, we have been able to highlight the impact of RSV at the constituen­cy level to support in understand­ing the burden RSV places on local health systems.

In the last pre-pandemic year in England (April 2019 to March 2020), children under five with RSV were admitted for a total of 107,451 bed days7 which, on average, cost local health services in each constituen­cy £139,792.7 Costs in some constituen­cies were as high as £478,119, however some were as low as £50,139.7 This variation shows the regional disparitie­s of the RSV burden.

Despite this burden, RSV is under-recognised by the general population.8 Furthermor­e, a lack of data on the prevalence of the virus means that the burden of RSV in infants and children could be greater than estimates suggest.9

Enhanced understand­ing of RSV could contribute to increased prioritisa­tion across the NHS, while also enhancing the care that infants and their families receive.

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