The Jewish Chronicle

Israel is starting to win the battle with cancer

With half of us expected to develop cancer at some point, recent breakthrou­ghs are huge

- By Alan Aziz Alan Aziz is CEO of Technion UK

WORLD CANCER Day — marked each year on 4 February — matters to everyone on the planet, given that one in two of us will develop the disease at some point in our lives. Even if we’re lucky enough not to get it ourselves, we will likely know someone who does. On a personal note, I am living first-hand with the very real impact cancer has on both the person suffering and their loved ones. My brother Mike was diagnosed three years ago. Whilst I remain optimistic, it has been and still is an incredibly difficult time for him and our families and my sympathies lie with anyone who has to go through this.

But there have been amazing breakthrou­ghs in how we discover and then treat cancer, especially in Israel.

Changing the way cancer is detected is being revolution­ised thanks to Ibex Medical Analytics, the creator of an Artificial Intelligen­ce-based diagnostic software.

A team of Israeli researcher­s has shed light on a key issue in treatment — the mechanisms that sometimes (and seemingly unpredicta­bly) result in successful chemothera­py but can also lead to the developmen­t of cancer metastasis, the main cause of cancer mortality. These findings could enable a combinatio­n of different drugs and treatments to reduce the chances of this happening.

Indeed, while chemothera­py still very much has a role in cancer treatment, the fact that it can also damage healthy cells has led many scientists to try to create more targeted approaches.

One of the biggest names to come out of Israeli cancer advancemen­ts is NanoGhost, which does just that. This groundbrea­king technology targets cancer cells with modified adult stem cells loaded with medicine. Meanwhile, OncoHost is the startup behind an AI-based blood test that will allow doctors to provide personalis­ed treatment plans to cancer patients, thanks to a prediction of how patients will respond to immunother­apy.

And the groundbrea­king discovery that cancer cells recruit the nerve cells around them both to stimulate and spread the disease has led another team of Israeli researcher­s to develop a revolution­ary breast cancer treatment that targets the tumour through the nerve cells by injecting anaestheti­c into the bloodstrea­m to paralyse the communicat­ion between the nerve and cancer cells. It doesn’t end there. Several other innovation­s — not directly related to the research, diagnosis or treatment of cancer but equally impactful nonetheles­s — are also leaving their mark on the disease.

PixCell’s HemoScreen is a quick, easy-to-use, portable and reliable instrument that enables real-time blood testing to be performed by anyone, anywhere, crucially before they set foot in the chemothera­py clinic. This saves patients time, energy and a considerab­le level of risk because it will identify the levels of their white blood cells — a vital metric before receiving the next dose of chemothera­py — saving the need to venture out unnecessar­ily. Results are also delivered within five minutes, a significan­t improvemen­t on the hours of waiting time using more traditiona­l methods, which is also a game-changer for the hospitals.

And when it comes to pain relief, patients have another team of Israeli researcher­s to thank, following the publicatio­n of research that medicinal cannabis is a highly effective tool and could be a viable alternativ­e to opioids, which are both addictive and can come with uncomforta­ble side effects.

Perhaps unsurprisi­ngly, all of these advancemen­ts are strongly linked to the Technion, with professors and graduates working tirelessly in the fight against cancer. This has been helped by the establishm­ent in 2016 of the Technion Integrated Cancer Centre, the first of its kind in Israel. Here, the extensive knowledge and vast experience in oncology accumulate­d at the university and its affiliated medical centres are combined, resulting in a dramatic change in the field of cancer medicine in Israel, through diagnosis, treatment and follow-up based on the principles of personalis­ed medicine. Cancer, we pray

that you have met your match.

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 ?? PHOTO: GETTY IMAGES ??
PHOTO: GETTY IMAGES

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