The Mail on Sunday

Pfizerchie­f:I’d give our jab to my 6-year-old

A year after the first Covid jab was given in the UK, Pfizer chief vows: We’ve stacks of vaccine ready to go when we get green light

- By Alex Lawson

THE boss of Pfizer in the UK is so certain of the safety of its Covid vaccine that he would allow his six-year-old daughter to have it now.

In an interview with The Mail on Sunday, Ben Osborn, who runs the British arm of the US drug giant and is head of the Associatio­n of the British Pharmaceut­ical Industry, said he has had ‘blunt’ conversati­ons with those opposed to vaccines.

Asked if Pfizer’s jab, developed rapidly with German partner BioNTech was safe, he said: ‘I think the biggest reassuranc­e I would give is that I would give the vaccine to my six-year-old daughter tomorrow if that were authorised.’

Experts and regulators in the UK are considerin­g whether to approve the vaccine’s use in five to 11-year-olds. Pfizer’s jab was last week approved for use on children as young as five by the European Medicines Agency and is also authorised for use in American children.

Mr Osborn said he has frequently been asked about the safety of the vaccine by sceptics concerned at the speed of its developmen­t – in just 259 days.

‘It’s frustratin­g but it’s part of the job,’ he said. ‘The most important message is, yes, it’s been done at speed but no corners have been cut.’

Pfizer has also moved to address concerns that existing vaccines may not offer protection against the new Omicron variant of the virus.

The firm said yesterday it had begun running ‘neutralisa­tion tests on the new Omicron variant of concern and expect to have initial data in the coming weeks’.

It added that if the variant escapes the protection of the vaccine, it expects ‘to be able to develop and produce a tailormade vaccine against that variant in approximat­ely 100 days’.

PFIZER’S UK boss Ben Osborn sprang out of bed last Monday morning with one burning thought in his mind. People his age – the 40 to 49-year-olds – had just become eligible for a Covid booster jab and he was determined to be among the first to get it.

‘Before I even had my coffee, I thought the system’s open, and within two minutes it was in the diary,’ says Osborn, 44, who signed up like everyone else.

He will receive the jab this week, exactly a year since the vaccine America’s Pfizer and German partner BioNTech developed was approved in the UK.

Osborn vividly remembers watching 90-year-old grandmothe­r Margaret Keenan receive the first Covid vaccine in the western world – a Pfizer jab in Coventry. It was a proud, careerdefi­ning moment, he explains, adding: ‘I’ve seen that clip umpteen times, I watched it back the other day and it made the hairs on the back of my neck stand up again.’

It’s also just over a year since Osborn first revealed to The Mail on Sunday that Pfizer had stacks of vaccines ready to go pending approval at its vast manufactur­ing site in Puurs, Belgium. Since then, there have been production squeezes due to upgrading those facilities, repeat UK Government orders for more doses and political bunfights over supplies.

Last week, emergence of the Omicron Covid variant has stoked concerns it may be able to evade the protection of current vaccines. Testing has already begun against the variant with initial data due in weeks.

The pharmaceut­ical giant is on track to produce more than three billion doses this year – up from an original target of 1.2billion.

Pfizer has said its mRNA technology gives it the flexibilit­y to develop new vaccine variants in as little as 100 days.

Osborn says, in the UK, the ‘Covid situation feels much more under control than it did 12 months ago’, due to the success of the vaccinatio­n programme.

He adds: ‘I’m incredibly proud of the small part Pfizer has played in supporting the NHS.

‘It has been a year like we’ve never experience­d before. It’s shown the importance of a thriving life sciences sector. Friends, family, neighbours, strangers in the street appreciate the work Pfizer brings to health and the economy.’

Not everyone has been so appreciati­ve. The clean-cut executive recounts having some ‘blunt’ conversati­ons with anti-vaccine advocates. He welcomes the debate, but says he typically questions the sources of their informatio­n compared with documented medical research.

‘It’s frustratin­g but it’s part of the job. The most important message is, yes, it’s been done at speed but no corners have been cut. I think the biggest reassuranc­e I would give is that I would give the vaccine to my six-year-old daughter tomorrow, if that were authorised.’

It’s a timely interventi­on for the executive who has spent two decades with Pfizer and was recently also appointed head of the Associatio­n of the British Pharmaceut­ical Industry.

Experts and regulators are considerin­g whether to approve its use in five to 11-year-olds, potentiall­y for a spring roll-out.

Last week, his rival, AstraZenec­a chief executive Pascal Soriot, was out in public proclaimin­g the efficacy of his own vaccine – specifical­ly that its widespread use in the UK may have limited the number of hospitalis­ations relative to parts of Europe, where its use had been restricted and cases are rising.

This time, Osborn declined to be drawn into a debate, with the analysis to back Soriot’s claim yet to be published.

But he hopes Britons will welcome their booster shots with the memory of last year’s festive restrictio­ns still fresh. ‘Clearly Christmas is going to be an important occasion for all of us but I’m very encouragin­g of everybody to come forward to get boosted not just for Christmas but beyond into next year.’

He says normality is returning, with a couple of recent trips to watch rugby at Twickenham and Cardiff. But he admits the pandemic has made life even harder for many – his elder son George, 14, has a rare form of epilepsy and has had his education at a special needs school disrupted, as well as his own ‘ultra running’ hobby. Discussion­s are ongoing over whether more jabs will be needed in 2022. He says, ‘We will likely see a need for some level of boosting in subsequent years’.

The UK has ordered 135million doses from Pfizer in total, more than any other jab, and Osborn assures that ‘supply of our vaccine is not an issue in the UK’.

A contract to produce the injection in Britain for the first time begins in April in Swindon.

Osborn is keen to harness the Covid momentum which has made the pharma firm – which operates from labs in Sandwich, Kent, in the UK – a household name.

He says: ‘We’ve shown that we could develop a vaccine in 259 days. So it’s about how we did that, and making sure we apply those learnings more broadly.’

He cites a promising rapidly developed pill aimed at Covid patients as a ‘potential gamechange­r’. And, in a message likely to cheer patients sidelined during the NHS’s Covid firefighti­ng, he adds: ‘We’re looking at how we can bring that same level of emphasis to other disease areas – the cancers, rare diseases, cardiovasc­ular disease, immunology.’

New developmen­ts could help Pfizer justify the huge profits it is expected to reap from the scramble by government­s to tackle a global emergency.

Vaccine revenues are expected to hit $36billion this year, up from $33.5 billion in 2020.

‘We didn’t take any Government funding, we invested some $2billion prior to even having a vaccine authorised and we have continued now to scale that research to other disease areas,’ Osborn says.

This month, Pfizer upped its forecasts for research and developmen­t spending by $400 million to $10.4 billion to $10.9 billion this year.

‘That allows us to be ready for future pandemics,’ Osborn says.

‘A year like we have never experience­d’

‘It allows us to be ready for future pandemics’

 ?? ?? DEFENDING THE SCIENCE: Pfizer’s UK manager Ben Osborn
DEFENDING THE SCIENCE: Pfizer’s UK manager Ben Osborn
 ?? ?? SHIFT: Ben Osborn says Pfizer is now able to widen its research into other diseases, including cancer. Left: Our story a year ago about its supplies
SHIFT: Ben Osborn says Pfizer is now able to widen its research into other diseases, including cancer. Left: Our story a year ago about its supplies
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