The Mail on Sunday

Eye jabs hailed as ‘big step’ in fighting sight loss

- By Ethan Ennals

THOUSANDS of people at risk of blindness could be spared monthly injections thanks to a new drug that slows the progressio­n of a common eye problem.

The medication, faricimab, could soon be offered to patients being treated for retinal vein occlusion (RVO), a leading cause of vision loss in the over-60s.

Current treatments for the condition have to be given via an injection into the eye once a month, but the new medication is so effective that trails suggest just three jabs a year are needed. Experts say this could be a ‘big step’ for patients suffering from the degenerati­ve disease.

RVO occurs when one of the small blood veins at the back of the eye becomes blocked by a clot. This causes blood and other fluids to leak into the retina, causing bruising and swelling.

While this will eventually go down, the leaking often continues, and over time can lead to blindness as the build up of fluid permanentl­y damages the eye.

The exact cause of RVO is unknown, but several conditions make it more likely, such as high

‘It would free up time and reduce waiting lists’

blood pressure, high cholestero­l, diabetes and smoking.

Studies suggest 50,000 Britons suffer from RVO every year, the majority of whom are aged over 60. Current injections are able to repair the damage to the veins, but these have to be administer­ed directly into the eye every month.

‘This means patients spend a lot of time coming into hospital,’ says Dr Christiana Dinah, consultant ophthalmol­ogist at London North West University Healthcare NHS Trust.

However, research suggests that faricimab, developed by

Swiss pharmaceut­ical company Roche, is as effective as the current drugs but allows for the time between treatments to be extended to up to four months.

Experts say this is because the treatment is also able to reduce the level of a compound in the blood called Ang2, which at high concentrat­ions can lead to leakage in blood vessels.

‘This feel like a big step forwards,’ says Dr Dinah. ‘Currently, thousands of hours are spent every year on the NHS carrying out these injections. If we could slash the number we had to carry out, it would free up more time for doctors and help reduce the worryingly large waiting lists we have.’

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