The Scotsman

Surge in GM animals used in experiment­s

But Scottish tests buck overall upward trend in UK

- Ilona amos

Thursday 24 OcTOber 2013 The number of geneticall­y modified animals used in live experiment­s in Scotland has jumped in the past year despite a drop in the total number of animals tested, according to new figures.

The use of GM animals – bred with DNA altered for testing – rose by nearly a third and made up nearly half of all lab animals used in Scotland. There was also a sevenfold increase in the use of monkeys since 2011.

The figures obtained

by

the British Union for the Abolition of Vivisectio­n (BUAV) also show a total of 623,194 animals were used in tests at universiti­es and commercial facilities north of the Border in 2012, a decrease of more than 3 per cent on the previous year.

The Scottish figures buck the UK trend, which saw a 9 per cent rise in the overall number of animals used in tests but a more modest increase in the use of animals bred to possess specific human genes.

The UK increase

comes

de- spite a commitment in the coalition agreement between the Tories and Lib Dems in 2010 to reduce the use of animals in scientific research, and ahead of legislatio­n that came into force in January, strengthen­ing a european Union directive.

Scientific studies last year in Scotland also used more dogs and rabbits than in 2011 – an increase of 62.5 per cent and 35 per cent respective­ly – as well as more than 12,000 animals with a harmful genetic mutation.

Researcher­s at Scottish

uni- versities experiment­ed on seals, rabbits, hamsters, guinea pigs, cattle, sheep, pigs, mice and rats as part of medical research into the effects of disease, pollution, diet and stress, but there is an increasing move towards replacing live testing with computer models and sophistica­ted cell culture systems.

Michelle Thew, chief executive of the BUAV, said: “Any decrease in the numbers of animals used in research is welcome. however, hundreds of thousands of animals continue to suffer and die in Scottish laboratori­es every year.

“In particular, we are alarmed to learn that during 2012 there were sharp increases in the numbers of geneticall­y modified animals, primates and dogs used. We need to see meaningful and lasting changes for animals in laboratori­es.”

A spokesman for Dundee University said all scientific procedures involving animals must be passed by its ethical review committee, which includes a vet, and all work is closely monitored and carried out under home Office licences.

“Animals are used for research only in instances where no alternativ­es are available,” he said. “The results of these studies are of great importance in better understand­ing and developing treatments for serious health problems, including Alzheimer’s, Parkinson’s disease, cancer, heart disease, diabetes, genetic disorders and infectious diseases.

“The university takes its ethical and legal responsibi­lities very seriously. All our work is carried out in accordance with the three Rs concept: reduction in the number of animals used, refinement of procedures so the least possible harm is done in collecting informatio­n, and the replacemen­t of animals with other research methods wherever possible.”

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