The Scotsman

Cancer drug could extend life by 9 months

Pancreatic treatment licensed for UK after trial success

- Lyndsay buckLand HEALTH CORRESPOnd­EnT

Thursday 6 February 2014 A nEW treatment for pancreatic cancer could soon be used to help extend the lives of scottish patients suffering the disease.

the drug Abraxane – also known as nab-paclitaxel – has been licensed for use in the UK after trials showed it helped patients live longer.

Experts and campaigner­s welcomed the launch of the drug, which it is hoped will be recommende­d for use by nHs scotland in the coming months.

More than 700 people a year in scotland are diagnosed with pancreatic cancer, with a similar number of deaths annually.

it is one of the most difficult cancers to treat, with patients often diagnosed at a late stage, by which time there are few treatment options.

in those diagnosed with advanced disease, life expectancy can be as little as three to six months. the cancer was highlighte­d recently after tV soap

featured a storyline in which the character Hayley Cropper decided to take her own life rather than face a painful death from the disease.

Despite the high death toll for pancreatic cancer, few new treatments have been identified in the last ten years.

But research last year showed that when Abraxane was used in combinatio­n with another cancer treatment – gemcitabin­e – the drug helped increase survival from 6.7 months to 8.5 months compared to using gemcitabin­e alone.

Further results then demonstrat­ed the injectable treatment could increase life expectancy by an average of 8.7 months.

one-year survival rates rose from 22 per cent to 35 per cent and at two years they doubled from 4 per cent to 9 per cent, according to a study published in the

last year. Professor Jeff Evans, director of the institute of Cancer sciences and professor of transla- tional cancer research at Glasgow University, said: “the results of the nab-paclitaxel study are a welcome additional option for patients with pancreatic cancer.

“treatment options for advanced disease have been very limited for more than a decade.

“therefore, nab-paclitaxel, which can improve survival in this disease, marks a step for- cancer cells. Abraxane has already been approved for use in patients with advanced breast cancer.

the drug, which costs £600 a month, has now been submitted by its makers Celgene for considerat­ion by the scottish Medicines Consortium, with hopes that patients will be allowed access to it as soon as possible.

Ali stunt, founder of Pancreatic Cancer Action, said: “the launch of Abraxane is a muchneeded addition in the treatment of metastatic pancreatic cancer and could really benefit eligible patients in the UK.

“this news will be a welcome advance for patients who are at a stage in their life when time is at an absolute premium.”

Alex Ford, chief executive of Pancreatic Cancer UK, added: “our support line assists patients and carers with questions around treatment and care on a daily basis.

“With so few treatment options available, we know they want access to new and effective treatments such as Abraxane. therefore, the launch of this medicine is greatly welcomed.”

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