The Scotsman

Diet linked to breast cancer spread

- By JOHN VON RADOWITZ brian.ferguson@scotsman.com

Aproteinbu­ildingbloc­kfound in many foods plays a key role in the spread of deadly breast cancer, research has shown.

Foods that are rich in the amino acid asparagine include dairy products, beef, poultry, eggs, fish, asparagus, beans, nuts, seeds, soy and whole grains.

The discovery by British and US scientists could pave the way to new treatments based on suppressin­g the molecule.

Using a drug and special diet to cut levels of asparagine greatly reduced the spread of an especially deadly form of breast cancer in mice, scientists found.

The animals had triplenega­tive breast cancer, which grows and spreads faster than other types and is notoriousl­y hard to treat.

Lead scientist Professor Greg Hannon, from the Cancer Research UK Cambridge Institute, said: “When the availabili­ty of asparagine was reduced, we saw little impact on the primary tumour in the breast, but tumour cells had reduced capacity for metastases [spread] in other parts of the body.

“This finding adds vital informatio­n to our understand­ing of how we can stop cancer spreading - the main reason patients die from their disease.

“In the future, restrictin­g this amino acid through a controlled diet plan or by other means could be an additional part of treatment for some patients with breast and other cancers.”

Newspapers in English

Newspapers from United Kingdom