The Scotsman

Edinburgh cancer firm launches with £3m funding

● Macomics spun out of University of Edinburgh ● Funds will help to develop novel immunother­apies

- By SCOTT REID sreid@scotsman.com

An Edinburgh-based company working on therapies to overcome the resistance of existing cancer treatments has launched with more than £3 million in seed funding.

Macomics, which boasts “world-leading expertise in macrophage biology”, has secured £3.2m in a financing round led by venture capital firm Epidarex Capital, with the Scottish Investment Bank, the investment arm of Scottish Enterprise, also investing.

The venture, which was spun out from the University of Edinburgh, will use the funds to develop novel immunother­apies designed to modulate macrophage­s, increasing the body’s immune defence against tumours.

Company formation and inlicensin­g of the technology has been facilitate­d by Edinburgh Innovation­s, the commercial­isation service for the University of Edinburgh.

Professor Jeffrey Pollard, founder director of Macomics and director of the MRC Centre for Reproducti­ve Health at the University of Edinburgh, said: “Decades of research into macrophage biology, particular­ly that of tumour-associated macrophage­s, have made it very clear to me that this is an area of significan­t untapped potential for the developmen­t of novel cancer therapeuti­cs.

“The creation of Macomics

based on the research of my group at the University of Edinburgh provides the team with an exciting opportunit­y to develop new effective cancer drugs against macrophage targets, that will bring real clinical benefit to many more patients suffering from cancer.”

Elizabeth Roper, partner at Epidarex Capital and investor director at Macomics, said: “We have known Jeff and his team and followed their world-leading research in macrophage biology for some time and are delighted to be leading this investment that triggers the launch of Macomics.

“This is one of the first investment­s from our new Epidarex Capital III UK fund that was announced recently.

“Despite the good progress that immunother­apies have brought to the treatment of cancer, addressing the hostile tumour environmen­t remains a major obstacle to achieving better clinical outcomes in a broader patient population.

“The approach that Macomics is pioneering has significan­t potential in the treatment of cancer, as recent deals in the tumour-associated macrophage area indicate.”

Robert Haigh, who joins Macomics as its chief executive, said: “This is an exciting time to be joining Macomics. I’d like to thank Epidarex, the Scottish Investment Bank and the University of Edinburgh.”

Kerry Sharp, director at the Scottish Investment Bank, added: “This is an extremely exciting immuno-oncology spin-out based on outstandin­g academic research. We are thrilled to support it.”

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