The Scottish Mail on Sunday

GENE TREATMENT FOR ADVANCED DISEASE

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PEOPLE with a highly aggressive type of lung cancer are set to benefit from a gene therapy drug after NHS spending watchdog NICE gave it the green light last week.

Patients in Scotland have benefited from the treatment atezolizum­ab, also known by the brand name Tecentriq, as an immunother­apy on the NHS since last August.

Health chiefs have approved tepotinib for patients in England, Wales and Northern Ireland after studies showed it slowed disease progressio­n and helped patients to live longer

– 20 months on average.

METex14 skipping alteration­s are seen in patients with nonsmall cell lung cancer, the most common form of the disease.

Targeted treatments such as tepotinib require genetic testing to determine eligibilit­y – and the NHS is developing genomic laboratory hubs across the UK to manage these assessment­s.

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