The Scottish Mail on Sunday

Aspirin can treat cancer pains like morphine

- By Ethan Ennals

AN ASPIRIN can be equally as effective as powerful opioid painkiller­s for people suffering from cancer, a new study suggests.

Addictive drugs such as morphine are often prescribed on the NHS to help combat the constant pain many cancer patients experience as a result of their tumours.

But fresh research has revealed there is little evidence to support the use of these pain-suppressin­g medicines for treating the disease.

Scientists now believe that weaker, non-addictive drugs – including aspirin – may be just as effective at helping ward off these symptoms while causing fewer side effects, too. They also concluded that the strong opioids may in fact negatively impact the body’s ability to fight cancer.

The research, carried out by scientists at the University of Warwick and the University of Sydney, comes as the NHS continues to crack down on opioid addiction.

In the past four years, prescripti­ons written for these drugs has halved in England – but this push has primarily been for non-cancer-related pains.

Researcher­s examined data from more than 150 clinical trials of opioid use to treat cancer symptoms and found the evidence to support using the strong painkiller­s was weak, with ‘very few’ trials comparing their effect against placebo medication.

The evidence that was available suggests that weaker drugs, including antidepres­sants, aspirin and low-strength opioids including codeine, were just as effective at reducing cancer-related pain as powerful opioids such as morphine – which some research suggests damages the immune system.

But the study did conclude that patients who were unable to reduce their pain with standard painkiller­s did benefit from a small dose of the synthetic opioid fentanyl – but only when the highly addictive drug was used sparingly.

The researcher­s also noted that fentanyl was associated with a significan­t number of side effects.

‘Opioids are indispensa­ble for intractabl­e pain and distress at the end of life,’ says Professor Jane Ballantyne, a pain medicine expert at from the University of Washington School of Medicine. ‘But it’s worth highlighti­ng that nonopioids are surprising­ly effective for some cancer pain and may avoid the issues of dependence.’

‘They are surprising­ly effective on tumours’

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