Western Mail

File a patent on T-cell discovery

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FANTASTIC news from Cardiff University, a discovery that opens up the possibilit­y to treat a wide variety of cancers; more specifical­ly, the research team at Cardiff together with their collaborat­ors have identified a specific type of T-cell that lab tests have shown can cure lung, skin, blood, colon, breast, bone, prostate, ovarian, kidney and cervical cancer in animal test models.

If I understand the technology correctly, this type of T-cell has been isolated from an animal’s blood, possibly modified, then grown in significan­t numbers outside the animal body (meaning in a specialise­d lab) and thence reintroduc­e in elevated numbers back into the animal to cure cancer in that animal.

So there is that caveat, what works on rodents modified to mimic human cancer patients may not, even after intensive research effort, work in human cancer patients.

Put another way, having a cure for cancer in mice is great news for mice, but is not particular­ly useful if it doesn’t work in humans!

But the ultimate goal remains to isolate this specific type of T-cell from a cancer patient’s blood, possibly modify them, then multiply in significan­t numbers outside the human patient and thence reintroduc­e the cells in larger numbers back into the patient to cure the patient of cancer. And repeat this process with other cancer patients.

This is all great news, but hopefully a MABs-type fiasco is not in the works here, wherein the past British discovery of Monoclonal Anti-Bodies led to the creation of tens of thousands of jobs, just not in the UK – all because a patent applicatio­n was not filed covering the MAB discovery.

American biotech companies grew fat off the unprotecte­d British discovery. (Inter alia, MABs are used to diagnose a plethora of diseases in human patients as well as animal pets.)

But I can’t believe a patent has not been filed on this latest T-cell discovery.

Wales is crying out for jobs – so why not create some here?

Christophe­r Wood (Born in Cardiff ) Arlington, Virginia, USA

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