Western Mail

‘Hepatitis rise may be linked to lockdown’

- ELLA PICKOVER and ISOBEL FRODSHAM Press Associatio­n newsdesk@walesonlin­e.co.uk

ALACK of exposure to a common virus during Covid restrictio­ns could be behind the surge in hepatitis cases among young children, experts have suggested.

Health officials are urgently investigat­ing the rise in cases which has led to more than 100 children needing hospital care and liver transplant­s for 10 British children.

Since the start of the year, 111 children – including 11 in Wales – have required hospital care for liver inflammati­on (hepatitis), with the majority of cases occurring among children under the age of five.

The leading line of inquiry is that the cases are being fuelled by a common virus called the adenovirus.

This virus usually causes mild illnesses including stomach upsets and colds.

But one theory is that the virus is leading to more severe illness among some children due to “susceptibi­lity, for example due to lack of prior exposure during the pandemic”, according to a technical briefing from the UK Health Security Agency (UKHSA).

Of 53 cases tested, 40 (75%) showed signs of adenovirus infection.

Routine NHS and laboratory data show that common viruses circulatin­g in children are currently higher than in previous years and there is a marked increase of adenovirus, particular in the one to four age group, the UKHSA said.

Other avenues being explored include whether a prior Covid infection followed by an adenovirus infection could be leading to more severe cases or co-infection with the two viruses.

Experts are also examining other possible causes including a new variant of adenovirus; potential exposure to drugs, toxins or environmen­tal factors; a new type of infection; or a new variant of the virus which causes Covid.

Covid-19 vaccinatio­n is not a contributi­ng factor as none of the cases investigat­ed so far have been vaccinated.

Of the confirmed cases, 81 live in England, 14 are in Scotland, 11 are in Wales and five are in Northern Ireland.

The cases are predominan­tly in children under five who showed initial symptoms of diarrhoea.

Parents have been urged to be alert to the signs and symptoms of hepatitis, including jaundice.

According to the World Health Organisati­on (WHO), as of April 21, 169 cases of acute hepatitis of unknown origin have been reported from 11 countries in Europe and America .

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