Western Morning News

Aim to double cancer survival rates by 2032

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SCIENTISTS believe they could double the survival of people with advanced cancer within a decade.

World-leading experts from the Institute of Cancer Research (ICR), London, and the Royal Marsden NHS Foundation Trust said that cutting-edge research will mean more people get cured while others live far longer.

Cancer scientists are increasing­ly gaining knowledge about what they describe as the “cancer ecosystem”. This is the complex system which allows cancer cells to thrive and is made up of cancer cells, the immune system and those molecules, cells and structures that surround tumours and help them grow.

Experts from the ICR and Royal Marsden believe by using several methods of attack they can make great strides in areas such as destroying cancer cells, boosting the body’s ability to fight cancer itself and cutting off the ways healthy cells are tricked into helping cancer survive. In one developmen­t, they hope to break the ability of cancer cells to instruct other cells in the body to come and support tumours.

Kevin Harrington, professor of cancer therapeuti­cs at the ICR and consultant at the Royal Marsden, told a briefing: “We recognise the fact that a lump of cancer in a patient is far more than simply a ball of cancer cells. It is a complex ecosystem.”

Launching a joint five-year research strategy, Professor Kristian Helin, chief executive of the ICR, said: “We have created a really exciting plan to unravel and disrupt cancer’s ecosystems, with new immunother­apies, drugs to target the tissue environmen­t, and clever new anti-evolution combinatio­ns.”

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