BFG 9000 – DOOM
The oldest gun on our list, first making its debut in 1993’s Doom, this granddaddy of destruction makes a welcome return in the 2016 Doom reboot. The BFG (it stands for big flippin’ gun, or something, obviously) is appropriately named. Cutting down the denizens of hell has never been so easy thanks to its massively powerful plasma beam, which (and here comes the ‘science’ bit) utilises ionised Argent Energy. It vaporises non-boss enemies with a single shot, and causes ‘splash damage’ to any demon unlucky enough to be standing nearby. Given this plasma powerhouse’s long-standing infamy, it should come as no surprise that it’s pretty much worshipped by the shady Union Aerospace Corporation.