Yorkshire Post

Gates pays for drive to beat killer flu

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A UNIVERSITY in Yorkshire has been awarded more than £300,000 by a charitable foundation set up by Bill and Melinda Gates to tackle flu.

The funding for the University of Sheffield will be used to see if vaccines can be created to protect children in parts of the world where the virus can prove fatal.

The university was given $400,000 (£306,000) from the foundation set up by Mr Gates, the co-founder of Microsoft, and his wife. Researcher­s are hoping to help develop a vaccine strategy in countries in sub-Saharan Africa where influenza contribute­s to some of the highest preventabl­e death rates in children.

Dr Thushan de Silva, who is based in the university’s Department of Infection, Immunity and Cardiovasc­ular Disease, said: “There is increasing evidence the first encounters we have with the influenza virus as a child can shape how susceptibl­e we are to different influenza throughout life.

“If we can find out if vaccinatin­g young children before they are exposed can provide broader and longer-term immunity it would open up new avenues to repurpose current seasonal vaccines within a broader universal influenza vaccine strategy and significan­tly advance the timeline to achieving this.”

Dr de Silva, who works with the London School of Hygiene and viruses

Tropical Medicine on the project, said: “It has the potential to be incredibly significan­t.”

Francesco Berlanda-Scorza, who is a project director at the Bill and Melinda Gates Foundation, said: “This important research will focus on elucidatin­g the different immunologi­cal responses to live attenuated vaccines, particular­ly early in life, in children who have already experience­d influenza infections and those who haven’t.”

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