Albany Times Union (Sunday)

At help clinic: ‘I saw God’

Ketamine increasing­ly used to treat severe depression and PTSD

- By Rachel Silberstei­n

ALBANY — The effects of the infusion were immediate for Faline O’Bannion. The 39-yearold’s husband even told her that her voice had changed.

The Ithaca resident started visiting ketamine infusion clinics in 2020 in Rochester and Syracuse, and now travels to Albany for maintenanc­e sessions.

O’Bannion has struggled with mood disorders since she was 14. Recently, her bipolar symptoms and obsessive compulsive disorder became debilitati­ng, forcing her to quit a career as a paralegal.

Ketamine has changed her life, O’Bannion said.

“Before the treatment, I felt that I was depression — that’s all there was to me. Now I can feel that the depression is separate from who I am. It’s not my entire being.”

While ketamine has a history of use in hospital settings as an analgesic and a nasal-spray form of the drug won U.S. Food and Drug Administra­tion approval in 2019 for use in treatmentr­esistant depression, ketamine infusion clinics and wellness centers take advantage of a federal loophole that allows off-label use of FDA-approved drugs. Facilities have proliferat­ed across the country in recent years, including in New York.

Known in its illicit form as “special K,” ketamine is a dissociati­ve drug that can provide rapid and effective relief for severe depression, pain and PTSD, studies show.

In the Capital Region, Dr. Philip Hansen — an Albany Med-trained anesthesio­logist — has been administer­ing ketamine infusions since 2018, drawing patients like O’Bannion from across the state.

Ketamine is billed as an al

ternative mental health treatment at a time proponents argue the traditiona­l mental health infrastruc­ture is failing. But critics say there is a danger of misuse and the industry should be better regulated.

Its rise coincides with a burgeoning movement in the U.S. to legalize psychedeli­cs like magic mushrooms and LSD for medicinal purposes. Both substances have long been classified by the FDA as Schedule I drugs, which indicates that there are no therapeuti­c uses for them and there is a high risk of misuse.

Ketamine is classified as a Schedule III drug, making it a controlled substance presumed to have fewer risks. It is not considered a psychedeli­c, although experts say it can have psychedeli­c effects.

It is used intravenou­sly in hospital emergency rooms for instant pain relief, especially in pediatric patients with broken bones that require setting.

Before starting his practice, Albany Ketamine Infusions, Hansen trained for two years under Dr. Glen Brooks, an early practition­er of ketamine infusion therapy, who has tried to standardiz­e the treatment.

Hansen had some early challenges with a former business partner and initially encountere­d skepticism from the medical establishm­ent.

“At that time, most of the people who were doing it were anesthesio­logists ... we knew the ins and outs of ketamine and the proper dosages,” Hansen said. “Psychiatri­sts pooh-poohed it and would discourage patients from trying it, because it had a reputation as a horse tranquiliz­er and a street drug.”

The drug gained acceptance in the mental health sector in 2019, when the FDA approved Spravato, a nasal spray for treatmentr­esistant depression that contains esketamine, a derivative of ketamine.

Now many of those skeptical doctors are prescribin­g Spravato, Hansen said.

By early 2021, the calls were rolling in. Hansen recently moved his practice to a larger location in Colonie and has hired an on-site licensed mental health counselor.

Ketamine used therapeuti­cally is not like the version available on the street, known for producing a “k-hole,” a ketamine effect that immobilize­s the user for several hours, according to Hansen. Street drugs also tend to be mixed with other substances like MDMA, amphetamin­e or cocaine.

Patients may experience disassocia­tion or believe they have died, but they can reframe those feelings with the help of a counselor, according to Hansen.

“They can turn it around and think, ‘yes, I died and came back and now I’m really able to embrace life,’” he said.

Hansen’s clients range from military veterans to teenagers who have attempted suicide. Many are referrals from local

“At that time, most of the people who were doing it were anesthesio­logists ... we knew the ins and outs of ketamine and the proper dosages. Psychiatri­sts pooh-poohed it and would discourage patients from trying it, because it had a reputation as a horse tranquiliz­er and a street drug.”

— Dr. Philip Hansen

psychiatri­sts and facilities that treat mental health disorders like Four Winds and Ellis Hospital.

Hansen also accepts walk-ins who have already tried traditiona­l therapy and medication, according to Kemi Campbell, who manages the clinic.

“We don’t promote escapism,” Campbell said. “You would have to have a diagnosis. We have turned maybe 300 patients away in the last year.”

▶

Donna Smith, a 62year-old from Stormville, who sees Hansen for chronic pain and severe depression, said her first infusion felt like a neardeath experience, but it transforme­d her.

“I saw God, I saw my loved ones and I was reassured that everything was going to be OK,” Smith said. “Unfortunat­ely, I can’t seem to get to that level again, but I felt so loved ... I was feeling very unloved. I didn’t even love myself.”

Smith said the isolation of the pandemic sent her spiraling into a despair that had her sleeping for days. She was forgetting things and was checked for Alzheimer’s. After each ketamine treatment, she became joyful and her sharpness returned, Smith said.

“If it wasn’t for Dr. Hansen, I probably would have said goodbye to this world,” Smith said.

Not all ketamine experience­s are easy. The sessions can be intense as suppressed memories are reactivate­d, according to Campbell.

“There is crying involved,

there is screaming involved. There are people who see dead relatives. We’ve had rape victims,” she said. “We don’t send anyone home unless they have a ride and they are emotionall­y OK. We have plenty of relaxation rooms. We have had people stay for lunch.”

Hansen and his staff work with patients on intention setting, select soothing music to accompany the experience, and offer after-care sessions with the counselor at an additional cost.

Some experts have voiced concern that many ketamine providers, which now include wellness centers and online vendors, are not providing adequate follow-up.

During the COVID -19 health crisis, federal regulation­s were relaxed to enable prescripti­ons of the drug without an inperson visit to a doctor. This led to a boom in online ketamine providers like Mindbloom, a ketamine subscripti­on service that sends customers a Bloombox containing “everything you need to complete your ketamine treatment from home.”

Subscriber­s receive ketamine lozenges that are dissolved under the tongue, detailed instructio­ns and have access to teletherap­y sessions.

According to Joshua White, founder and executive

director of Fireside Project, which operates a hotline for people struggling to process experience­s with psychedeli­cs and other alternativ­e treatments, the hotline has seen a surge in calls about ketamine in the last two years.

To be successful, ketamine requires intention setting and hard work — with most of the work beginning after the treatment, White said. Yet, many providers don’t provide after-care, or provide it at an additional cost.

“Ketamine can cause deep and powerful emotions and traumas to surface,”

White said. “It’s essential that clinics provide patients with robust opportunit­ies to process and integrate whatever has arisen for them. Just as stitches and physical therapy are an essential part of many surgeries, so too is integratio­n a critical part of a ketamine experience.”

The absence of posttreatm­ent counseling reduces the likelihood that the patient will heal, White said.

Ketamine therapy is not cheap. At Hansen’s clinic, it costs about $400 for an hourlong session. Time with the therapist is an additional $100 per hour, though it is sometimes covered by insurance.

Six sessions over the course of a month are recommende­d for maximum efficacy, according to Hansen. The effects also tend to wear off and most patients will require monthly ketamine boosters.

O’Bannion and Smith said the cost of treatment has been a significan­t source of stress. For O’Bannion, the price has caused her to delay booster treatments, which has resulted in waves of depression.

Smith said she stopped seeing her regular therapist in order to pay for the infusions.

“I had to find the money,” she said. “I didn’t care how broke I became. I stopped shopping, I stopped everything.”

Hansen said he works with patients on cost by providing prescripti­ons for less-potent Spravato and at-home treatments that may be covered by health insurance.

For pain management, Smith said she takes daily at-home ketamine tablets that are partially covered by her insurance.

Ketamine is not for everyone, Hansen said. It’s not recommende­d for people with schizophre­nia or seizure disorders. Hansen also won’t treat someone who is addicted to drugs or actively suicidal.

“It’s not a crisis center,” he said. “Those patients need proper care and should be going to the hospital.”

Some Type A personalit­y types may also struggle with ketamine infusion, according to Hansen.

“People who are very anxious and can’t handle the feeling that your body is not quite your own — it intensifie­s their anxiety. Those are the people I weed out,” Hansen said. “There is a certain buy-in with the treatment ... you have to understand that this is what’s going to happen and it’s for the good.”

Ketamine can cause deep and powerful emotions and traumas to surface.”

— Joshua White

 ?? ?? Dr. Philip Hansen, seated, gathers with other profession­als at his office, Albany Ketamine Infusions, in Albany. Standing from left are Jennifer Sciuto, LPN, psychother­apist Sativa Bigelow, practice and operations manager Kemi Campbell and Noah Norstein, RN.
Dr. Philip Hansen, seated, gathers with other profession­als at his office, Albany Ketamine Infusions, in Albany. Standing from left are Jennifer Sciuto, LPN, psychother­apist Sativa Bigelow, practice and operations manager Kemi Campbell and Noah Norstein, RN.
 ?? Photos by Jim Franco / Times Union ?? Julie Whitten, intake reception specialist at Albany Ketamine Infusions.
Photos by Jim Franco / Times Union Julie Whitten, intake reception specialist at Albany Ketamine Infusions.
 ?? ?? Albany Ketamine Infusions, as seen from outside.
Albany Ketamine Infusions, as seen from outside.

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