Seahawks at 49ers

7:25 p.m. Central CBS/NFL LINE — Seahawks by 6 ½

LAST MEETING Seahawks beat 49ers 17-7, Dec. 14, 2014 LAST WEEK Seahawks lost to Panthers 27-23; 49ers beat Ravens 25-20 RANKINGS Seahawks: offense 15, defense (4); 49ers: offense (30), defense (31) NOTES Seahawks have won three in a row and five of six in the rivalry, including playoffs, and swept last season’s two meetings. … Seattle looks to improve its prime-time record to 14-2 since 2010 under Pete Carroll, having outscored opponents 397-191. It’s the team’s third prime-time game of year and first of two road games ahead of a bye week. The Seahawks lost on Sunday night, Sept. 20, at Green Bay and before that their last loss in prime time came at San Francisco on a Thursday night, Oct. 18, 2012. … Seahawks are 13-8 in last 21 road games dating to 2012. … Seattle has led in the fourth quarter all six games this year — outscored 61-27 in fourth quarter and overtime, 40-3 in past three games. … Seahawks CB Richard Sherman has 24 career interceptions and needs one to reach 10th place for most interceptions during a player’s first five seasons since 1970. Sunday marks his 71st game. … 49ers QB Colin Kaepernick is 1-5 in six starts vs. Seattle including playoffs, with 3 TDs, 9 interceptions, 18 sacks, a 53.3 percent completion rate and 54.1 percent passer rating. Against everybody else, including in postseason, he’s 30-15, completing 60.9 percent of throws for 60 touchdowns to 22 interceptions, with 94.0 quarterback rating. … WR Anquan Boldin has two consecutive games with 100 yards receiving and is trying to to become first 49ers player with three consecutive since Hall of Famer Jerry Rice in Weeks 15-17 in 1995.