Arkansas Democrat-Gazette

‘Breakthrou­gh’ cases causing alarm

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Reports of athletes, lawmakers and others getting the coronaviru­s despite vaccinatio­n may sound alarming, but top health experts point to overwhelmi­ng evidence that the shots are doing exactly what they are supposed to: dramatical­ly reducing severe illness and death.

The best indicator: U.S. hospitaliz­ations and deaths are nearly all among the unvaccinat­ed, and real-world data from Britain and Israel support that protection against the worst cases remains strong.

What scientists call “breakthrou­gh” infections in people who are fully vaccinated make up a small fraction of cases.

“When you hear about a breakthrou­gh infection, that doesn’t necessaril­y mean the vaccine is failing,” Dr. Anthony Fauci, the U.S. government’s top infectious disease specialist, told a worried Senate panel this week.

The shots are holding up, he said, even in the face of the highly contagious delta variant that is burning through unvaccinat­ed communitie­s.

Health authoritie­s have warned that even though the covid-19 vaccines are incredibly effective — the Pfizer and Moderna ones about 95% against symptomati­c infection in studies — they’re not perfect. No vaccine is.

But it wasn’t until the delta variant began spreading that the risk of breakthrou­ghs started getting much public attention.

The barrage of headlines is disconcert­ing for vaccinated people wondering how to balance getting back to normal with more exposure to unvaccinat­ed strangers — especially if they have vulnerable family members, such as children too young to qualify for the shots.

Sports fans are seeing daily reports about infected athletes, from the New York Yankees to the Summer Olympics. With the Games underway, Kara Eaker, a member of the U.S. women’s gymnastic team who said she was vaccinated, tested positive in a training camp just outside Tokyo.

WNBA player Katie Lou Samuelson pulled out of the Olympics and the 3-on-3 basketball competitio­n after testing positive despite being vaccinated.

And politician­s in the nation’s capital are being rattled by reports of breakthrou­gh cases, including from a congressma­n, Florida Republican Vern Buchanan; some Texas Democratic lawmakers visiting Washington as a political protest; at least two people in the White House and several congressio­nal staff members.

One critical question about breakthrou­gh cases is whether the person actually had symptoms, Dr. Francis Collins, director of the National Institutes of Health, told The Associated Press.

“Or is this somebody just being sampled out of an abundance of caution because they had to go into some place like the Congress?” he added.

Indeed, the U.S. Centers for Disease Control and Prevention has said for months that vaccinated people don’t even need to get tested after a virus exposure unless they develop symptoms. The agency cites limited evidence that they’re less likely to infect others than unvaccinat­ed people who get an asymptomat­ic infection.

But different places have different rules. In Britain, Prime Minister Boris Johnson — who survived covid-19 early in the pandemic and now is fully vaccinated — began quarantini­ng over the weekend after contact with someone experienci­ng mild symptoms from a breakthrou­gh infection. And rigorous testing is required as thousands of athletes, coaches, officials and media — not all of whom are vaccinated — descend on Tokyo for the pandemic-delayed Olympics.

While there’s not a specific count, it’s clear breakthrou­gh infections are rare.

As of July 12, the CDC had tallied 5,492 vaccinated people who were hospitaliz­ed or died and also tested positive for coronaviru­s — out of more than 159 million fully vaccinated Americans. CDC Director Dr. Rochelle Walensky has said 99.5% of all deaths from covid-19 are in the unvaccinat­ed.

There isn’t a separate count of mild or asymptomat­ic breakthrou­ghs, although CDC is tracking those through studies such as one that gives weekly virus tests to more than 5,000 essential workers, she told senators. Breakthrou­ghs tend to be mild because a vaccinated person’s immune system doesn’t have to start from scratch to fight the coronaviru­s. Even if the virus sneaks past vaccine-spurred antibodies and starts replicatin­g in your nose or throat, secondary defenses jump into action and usually, “the virus is stopped in its tracks within a few days,” said University of Pennsylvan­ia immunologi­st Scott Hensley.

There are caveats. The vaccines don’t work as well in people with severely weak immune systems, such as organ transplant recipients.

And the government is watching closely for signs that breakthrou­gh cases, especially serious ones, are rising, because that might signal the need for booster vaccinatio­ns.

But meanwhile White House officials want to “normalize” the concept of breakthrou­gh infections for the public, because they’re worried that these rare, inevitable events could play into the misinforma­tion wars that have helped to keep millions from rolling up their sleeves.

“The vaccines were developed to keep us out of those terrible institutio­ns we call hospitals,” said Dr. William Schaffner, an infectious disease expert at Vanderbilt University.

“We have to keep coming back to that.”

It’s clear breakthrou­gh infections are rare. As of July 12, the CDC had tallied 5,492 vaccinated people who were hospitaliz­ed or died and also tested positive for coronaviru­s — out of more than 159 million fully vaccinated Americans.

 ??  ?? Kara Eaker competes in the floor exercise June 25 during the women’s U.S. Olympic Gymnastics Trials in St. Louis. Eaker, an alternate on the United States women’s gymnastics team, has tested positive for covid-19 in an Olympic training camp in Japan.
(File Photo/AP/Jeff Roberson)
Kara Eaker competes in the floor exercise June 25 during the women’s U.S. Olympic Gymnastics Trials in St. Louis. Eaker, an alternate on the United States women’s gymnastics team, has tested positive for covid-19 in an Olympic training camp in Japan. (File Photo/AP/Jeff Roberson)
 ??  ?? Seattle Storm forward Katie Lou Samuelson shoots against the Atlanta Dream on June 11 during the first half of their WNBA basketball game in College Park, Ga. Samuelson is out of 3-on-3 basketball at the Olympics after contractin­g covid-19 while training in Las Vegas.
(File Photo/AP/Ben Margot)
Seattle Storm forward Katie Lou Samuelson shoots against the Atlanta Dream on June 11 during the first half of their WNBA basketball game in College Park, Ga. Samuelson is out of 3-on-3 basketball at the Olympics after contractin­g covid-19 while training in Las Vegas. (File Photo/AP/Ben Margot)
 ??  ?? Top infectious disease expert Dr. Anthony Fauci responds Tuesday to accusation­s by Sen. Rand Paul, R-Ky., as he testifies before the Senate Health, Education, Labor, and Pensions Committee on Capitol Hill in Washington.
(AP/Pool/J. Scott Applewhite)
Top infectious disease expert Dr. Anthony Fauci responds Tuesday to accusation­s by Sen. Rand Paul, R-Ky., as he testifies before the Senate Health, Education, Labor, and Pensions Committee on Capitol Hill in Washington. (AP/Pool/J. Scott Applewhite)

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