Asbury Park Press

Can aspirin use prevent colon cancer and strokes?

- The People’s Pharmacy Joe Graedon and Teresa Graedon

My father had colon cancer, and I have had polyps myself, including a precancero­us one. Consequent­ly, I might be an ideal candidate for daily aspirin to prevent colon cancer.

However, my family also has a huge history of stroke. In a previous column, you addressed aspirin therapy as a rather significan­t risk factor for stroke. I don’t know how to weigh the risk/benefit ratio of aspirin therapy, considerin­g these two factors. Can you help?

Before your physician can make any recommenda­tions, it is essential to know what kind of strokes your family has experience­d. If they were primarily ischemic strokes caused by a clot in a blood vessel of the brain, then aspirin might be protective.

If, on the other hand, they were hemorrhagi­c strokes caused by bleeding into the brain, aspirin might pose an unacceptab­le risk.

A recent study in the journal Cancer (April 22, 2024) explains how aspirin helps the immune system track down colorectal cancer cells and reduce the risk for metastases. A comprehens­ive review of prior research concluded that people taking aspirin were significan­tly less likely to develop cancer in their digestive tracts (Annals of Oncology, April 1, 2020).

Only your physician can determine if the benefits of regular aspirin use outweigh the risk. This is not a do-ityourself project.

I have prediabete­s and need to lose some weight to qualify for back surgery. That’s why my doctor prescribed Ozempic.

The first month, I was on a low dose and had minor nausea. After it was increased to 0.5 milligrams a week, I suffered persistent nausea and constipati­on. I could barely stand to look at food.

This drug limited my social interactio­ns for fear of throwing up. I felt like I was in my first trimester of pregnancy, so I could not continue. What other options will help me control my blood sugar levels?

Some people find the nausea, vomiting, diarrhea or constipati­on associated with semaglutid­e (Ozempic) intolerabl­e. There are many other ways to manage blood sugar, though, including older medication­s such as metformin.

You can learn about the pros and cons of diabetes drugs and non-drug approaches in our “eGuide to Preventing and Treating Diabetes.” This online resource can be found under the Health eGuides tab at www.PeoplesPha­rmacy.com.

I read that SLS could cause canker sores. I have found a toothpaste without SLS called Squigle. I tried it and love it. Since I began using it, I’ve not had a single canker sore.

Like toothpaste, shampoo often contains SLS. I used to have a lot of what my mother would call “creeping crud” on my scalp. Nothing helped much; anti-dandruff shampoos worked but only if I used them very frequently. Using no-SLS shampoos has gotten rid of the crud for years.

We checked the ingredient­s of Squigle. It is indeed free of sodium lauryl sulfate (SLS). In fact, it contains 36% xylitol, a natural sugar from birch trees that combats bacteria that form plaque on teeth.

SLS is a surfactant. That means that it is a foaming agent, commonly found in body care products like shampoos. The detergent action may be irritating to the skin. That’s probably why some people report canker sores after using SLS-containing toothpaste (Dermatitis, SeptemberO­ctober 2021). Other people may experience scalp irritation upon exposure to SLS in shampoos.

In their column, Joe and Teresa Graedon answer letters from readers. Write to them in care of King Features, 628 Virginia Drive, Orlando, FL 32803, or email them via their website: www.PeoplesPha­rmacy.com. Their newest book is “Top Screwups Doctors Make and How to Avoid Them.”

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