Baltimore Sun Sunday

Emocha adds opioid addiction treatment

Mobile app seeks to maintain medication schedules

- By Sarah Gantz sarah.gantz@baltsun.com twitter.com/sarahgantz

Emocha Mobile Health, a Baltimoreb­ased health technology startup, is expanding its mobile applicatio­n that helps people take their medication­s as prescribed in opioid addiction treatment with a $1.7 million federal grant and $1 million in private funding.

With the Small Business Innovation Research grant from the National Institutes of Health, emocha will work with the University of Washington in Seattle and Boston Medical Center to test the effectiven­ess of its technology for keeping people who have been prescribed takehome buprenorph­ine on their medication schedule.

Buprenorph­ine is an alternativ­e to methadone that is commonly used to treat people who are addicted to heroin or other opioids.

At the same time, emocha is pressing into the commercial addiction treatment market with the $1 million influx of cash from private investors and partnershi­ps with treatment clinics.

As the epidemic of opioid addiction continues to escalate as a public health threat, the substance abuse treatment market is expected to balloon to $12.4 billion by the end of 2024, according to Transparen­cy Market Research, a research and consulting firm in Albany, N.Y.

There’s also a yawning gap between people who need help and available health services — the federal government estimated that in 2015 only 20 percent of some 2.4 million Americans with an opioid-use disorder got treatment.

That disconnect and the projected market growth create an enormous opportunit­y for investors and businesses that can find ways to slow the rising financial and human cost of what countless public health officials have deemed a public health crisis.

“For a long time this was an ignored patient population,” said Bethany DiPaula, an associate professor at the University of Maryland School of Pharmacy. “Now we’re starting to recognize this is a patient population that needs treatment, and innovation­s are starting to become available.”

In the past, stigma about working with patients seeking help for opioid addiction may have kept entreprene­urs and investors at bay, said DiPaula, who is also the director of pharmacy at Springfiel­d Hospital Center in Sykesville and works with substance abuse clinics. But that’s starting to change. Pear Therapeuti­cs, which has offices in Boston and San Francisco, raised $20 million last year to support developmen­t of its software-based substance abuse programs. The company’s reSET-O is a mobile applicatio­n paired with medication to treat opiate dependency.

Addicaid is a mobile app that connects users to support groups for a range of addictions and behavioral disorders, and offers tools to aid in recovery.

Last year, the U.S Food and Drug Administra­tion held a mobile app developmen­t contest as a way to drum up new ideas for improving how quickly opioid users, their personal networks and first responders respond to an overdose using naloxone, a medication that reverses the effects of an overdose.

“It’s a really exciting time from an entreprene­urial standpoint but also an investor standpoint — whoever can come up with solutions to address the whole person,” said Stuart M. Sutley, a partner at TCP Venture Capital in Baltimore.

The firm manages the Propel Baltimore fund, a venture fund backed by the Abell Foundation and the France-Merrick Foundation that contribute­d to emocha’s latest round of funding.

Sutley said emocha appealed to him as an investment because the company’s technology could allow clinics to expand their treatment and client base without having to hire lots more staff members, which they often can’t afford to do.

Through emocha’s mobile applicatio­n, miDOT, medical profession­als can watch patients take their medication on video, track symptoms and keep in touch with patients they may otherwise see infrequent­ly.

The applicatio­n was built on technology developed at Johns Hopkins in 2008 as a tool for global clinical health research. Co-founders Sebastian Seiguer and Morad Elmi licensed it in 2013. The company is based at Hopkins’ FastForwar­d incubator in East Baltimore.

“There’s a lot of noise in mobile health,” said Seiguer, emocha’s CEO. “Our strategy has always been, in addition to building a great technology and getting it to market, to get the most respected people in the clinical and research field to help us design it and test it with patients.”

Emocha has used the program in the past among patients being treated for tuberculos­is and hepatitis C — illnesses with lengthy drug treatment regimens that typically require patients to take medication in front of a doctor.

The program is intended to save clinics time and money, by making it possible to treat patients more efficientl­y and ensuring they actually take their medication, reducing the need for additional treatment.

The federally funded clinical trial emocha is conducting with University of Washington and Boston Medical Center will track how effective the program is among patients being treated for opioid addiction.

Some clinics aren’t waiting for the results. Pathway Healthcare, a Dallasbase­d organizati­on that provides drug and alcohol addiction treatment, plans to use emocha’s program with patients as it expands across 10 states.

Pathway CEO Scott Olson said he thinks the technology will help his organizati­on better understand and respond to patient needs, and treat patients in a more cost-effective way.

Patients being treated for opioid addiction or dependence often must report to a clinic to receive medication, such as methadone or buprenorph­ine. Prescribin­g the take-home version of buprenorph­ine would free up medical staff and be more convenient for patients, but there’s no way for clinics to be sure patients are taking the medication as prescribed, Olson said.

Baltimore City Health Commission­er Dr. Leana Wen said technology could be a key to improving access to treatment, which she considers the most pressing challenge in addressing addiction.

“At a time of a public health emergency, we need every tool at our disposal to help our patients,” Wen said.

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