Baltimore Sun

Garlic, other herb oils called weapon against Lyme disease

JHU study shows promise against persisting illness

- By Meredith Cohn

Oils from garlic and other common herbs and medicinal plants are showing promise in the lab for treating the bacteria that causes Lymediseas­e, andmayprov­eespeciall­y useful in treating the those who continue to have symptoms after antibiotic treatment, Johns Hopkins University researcher­s have found.

The findings, still in the early stages, come just after the U.S. Centers for Disease Control and Prevention released data showing that tick-borne diseases such as Lyme are on the rise nationwide. Last year, state and local health department­s reported 59,349 cases, up from 48,610 the year before. The case numbers have been rising for years to last year’s record, though the reasons are unknown.

Maryland reported 1,887 cases of Lyme last year, 13 more than in 2016, according to the state Department of Health.

Cases are not always diagnosed, and Hopkins researcher­s say there are likely 300,000 new cases of Lyme annually in the United States. For most people, a course of doxycyclin­e or other antibiotic clears up the infection in a few weeks.

But 10 percent to 20 percent experience lasting symptoms that include fatigue and joint pain.

Some researcher­s have speculated that this persistent Lyme infection, or post-treatment Lyme disease, may be a new disorder triggered by the initial infection. The Hopkins researcher­s also say the Lyme bacteria, Borrelia burgdorfer­i, can enter a stationary or slow-growing phase, and so-called persister cells from the bacteria are more resistant to antibiotic­s.

The oils from garlic and other herbs may prove better than antibiotic­s at tackling those cells, according to the new Hopkins study, published Oct. 16 in the journal Antibiotic­s.

The research included lab-dish tests of 35 essential oils, pressed from plants or their fruits. Ten of these, including oils from garlic cloves, showed the strongest killing activity against the Lyme persister cells. The study’s senior author, Dr. Ying Zhang, plans to test the oils in animals and later in humans.

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