Chattanooga Times Free Press

Trump taking malaria drug to ward off virus

- BY ZEKE MILLER AND DARLENE SUPERVILLE

WASHINGTON — President Donald Trump said Monday that he is taking a malaria drug to protect against the new coronaviru­s, despite warnings from his own government that it should only be administer­ed for COVID-19 in a hospital or research setting because of potentiall­y fatal side effects.

Trump told reporters he has been taking the drug, hydroxychl­oroquine, and a zinc supplement daily “for about a week and a half now.” Trump spent weeks pushing the drug as a potential cure or prophylaxi­s for COVID-19 against the cautionary advice of many of his administra­tion’s top medical profession­als. The drug has the potential to cause significan­t side effects in some patients and has not been shown to combat the new coronaviru­s.

Trump said his doctor did not recommend the drug to him, but he requested it from the White House physician.

“I started taking it, because I think it’s good,” Trump said. “I’ve heard a lot of good stories.”

The Food and Drug Administra­tion warned health profession­als last month that the drug should not be used to treat

COVID-19 outside of hospital or research settings, because of sometimes fatal side effects. Regulators issued the alert for the drug, which can also be used to treat lupus and arthritis, after receiving reports of heartrhyth­m problems, including

deaths, from poison control centers and other health providers.

Trump dismissed reports of side effects, saying, “All I can tell you is, so far I seem to be OK.”

At least two White House staffers tested positive for COVID-19 earlier this month, sparking concerns about the steps taken by the administra­tion to protect the president and sending Vice President Mike Pence and other officials into varying forms of self-isolation.

The White House has since mandated that those in the West Wing wear face coverings and has introduced daily testing for the virus for the president, vice president and those they come in close contact with.

Trump last underwent an “interim” checkup in a November visit to Walter Reed National Military Medical Center that was not noted on his public schedule. His last complete physical took place in February 2019.

Trump has repeatedly pushed the use of the drug with or without the antibiotic azithromyc­in, but no large, rigorous studies have found them safe or effective for preventing or treating COVID-19.

Two large observatio­nal studies, each involving around 1,400 patients in New York, recently found no benefit from hydroxychl­oroquine. Two new ones published Thursday in the medical journal BMJ reached the same conclusion.

One, by French researcher­s, gave 84 hospitaliz­ed patients the drug and 97 others the usual care. There were no difference­s in the odds of death, need for intensive care or developing severe illness.

The other study from China was a stricter test: 150 adults hospitaliz­ed with mild or moderate illness were randomly assigned to get hydroxychl­oroquine or usual care. The drug made no difference in rates of clearing the virus or time to relief of symptoms, and they brought more side effects.

In April, the National Institutes of Health launched a study testing hydroxychl­oroquine versus a placebo drug in 500 hospitaliz­ed COVID-19 patients. Last week, NIH announced another study to see if hydroxychl­oroquine plus azithromyc­in can prevent hospitaliz­ation or death in people with mild to moderate illness. About 2,000 U.S. adults with confirmed coronaviru­s infections and symptoms such as fever, cough or shortness of breath will get the drugs or placebo pills.

U.S. prescripti­ons for hydroxychl­oroquine surged roughly 80% in March to more than 830,000 compared with same period in the prior year, according to data tracking firm IQVIA. That jump in prescribin­g came before the federal government accepted nearly 30 million doses of the drug donated to the strategic national stockpile by foreign drugmakers.

Newspapers in English

Newspapers from United States