Chattanooga Times Free Press

AstraZenec­a to buy Alexion for $39B

- BY MICHAEL J. DE LA MERCED

LONDON — Drugmaker AstraZenec­a agreed Saturday to buy Alexion, a biopharmac­eutical company, for $39 billion in cash and stock, as corporate giants resume big-ticket takeovers, even amid the pandemic.

The deal comes as AstraZenec­a is in the final stages of testing a COVID-19 vaccine that it is developing with the University of Oxford, one of the most prominent candidates — but which has also faced questions about its effectiven­ess.

Through the deal for Alexion, the biggest by a health care company this year, AstraZenec­a will bolster its offerings for rare diseases like blood disorders. It comes as corporate boards have continued to regain confidence after battening down the hatches in the early stages of the pandemic.

As stock markets have soared and debt financing remains cheap because of central bank policies, companies have resumed their quest for growth and scale — including through acquisitio­ns.

Under the terms of the deal, AstraZenec­a will pay $60 in cash and 2.1243 of its American depositary receipts for each of Alexion’s shares. That amounts to $175 a share, a nearly 45% premium to Alexion’s closing price Friday.

AstraZenec­a, which is headquarte­red in Cambridge, England, has turned its focus in recent years to cancer treatments, after its previous bestsellin­g drugs, like the cholestero­l treatment Crestor, lost their patent protection­s. In July, the company agreed to pay up to $6 billion to partner with Japanese drugmaker Daiichi Sankyo on a potential treatment for lung and breast cancers.

But AstraZenec­a has been best known in recent months for its work in a different area: COVID-19 vaccines, where it is teaming up with researcher­s from Oxford.

The two announced in late November that their coronaviru­s vaccine appeared to be up to 90% effective. Unlike some other leading vaccine candidates, including those from Pfizer and Moderna, the AstraZenec­a offering can be quickly produced in vast quantities, would cost only a few dollars per dose and is easy to store for long periods.

But scientists and industry experts almost immediatel­y began to raise questions after AstraZenec­a acknowledg­ed a key mistake in the vaccine dosage received by some study participan­ts, and now the issue is whether its vaccine’s efficacy will hold up under additional testing.

The deal for Alexion will help AstraZenec­a expand in another sector: immunology, where treatments can be highly lucrative for their makers. Alexion, which is based in Boston, is known for focusing on combating rare diseases. Its top drugs include Soliris and Ultomiris, which treat blood disorders.

Each costs several hundred thousand dollars per year. That underpins AstraZenec­a’s expectatio­n that the deal will help lead to double-digit sales increases through 2025 and let it raise its dividend payouts.

“Alexion has establishe­d itself as a leader in complement biology, bringing life-changing benefits to patients with rare diseases,” Pascal Soriot, AstraZenec­a’s chief executive, said in a statement.

The company has faced pressure in recent years from Elliott Management, the $41 billion activist investment firm run by financier Paul E. Singer. The hedge fund has repeatedly criticized Alexion over its business strategy, including multibilli­on-dollar corporate takeovers that proved disappoint­ing. (The day Alexion announced its acquisitio­n of Portola Pharmaceut­icals in May, its stock fell sharply, signaling investor discontent with the deal.)

Shortly after, Elliott demanded that the drugmaker sell itself. A spokespers­on for the hedge fund declined to comment Saturday.

Shareholde­rs in Alexion are expected to own about 15% of the combined company after the deal closes, which is expected by next September, pending approval by regulators and investors in both companies.

 ?? AP FILE PHOTO/EUGENE HOSHIKO ?? Workers walk out from the AstraZenec­a building in Shanghai, China. The Cambridge, England-based pharmaceut­ical company which is involved in developmen­t of a potential COVID-19 vaccine, said Saturday it is acquiring Boston-based drug developer Alexion Pharmaceut­icals Inc. in a deal worth $39 billion.
AP FILE PHOTO/EUGENE HOSHIKO Workers walk out from the AstraZenec­a building in Shanghai, China. The Cambridge, England-based pharmaceut­ical company which is involved in developmen­t of a potential COVID-19 vaccine, said Saturday it is acquiring Boston-based drug developer Alexion Pharmaceut­icals Inc. in a deal worth $39 billion.

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