Chicago Sun-Times (Sunday)

JUNK FOOD CRAVINGS TIED TO HORMONES, CIRCADIAN CYCLE

- DR. ELIZABETH KO DR. EVE GLAZIER Dr. Eve Glazier and Dr. Elizabeth Ko are internists at UCLA Health.

Dear Doctors: Is there some reason I crave junk food when I’m really tired? I’m working double shifts. If I don’t sleep enough, all I want is donuts and pizza. My husband says it’s because they’re my favorite foods, and they’re easy.

Dear Reader: Research has found a link between sleep and the endocrine system, and the connection plays out with two hormones in particular: ghrelin and leptin. Each has an important role in regulating hunger.

Ghrelin, which stimulates appetite, is produced and released mainly from the tissues of an empty stomach. Its roles include facilitati­ng fat storage, regulating blood sugar and helping with memory retention.

It also makes you feel hungry and has come to be known as the hunger hormone.

Leptin suppresses appetite. It’s stored in adipose tissue — body fat. Once released, it circulates in the blood and reaches the brain. One of leptin’s jobs is to signal the brain to create the feeling of being full.

The ebb and flow of these hunger hormones is tied to the cycle of daylight and darkness — the circadian cycle that cues so many of the body’s essential functions.

When you’re sleep-deprived, you’ve fallen out of sync with your circadian rhythms. This has the effect of suppressin­g the leptin levels that let you know you’re full and increasing the secretion of ghrelin, which amps up appetite and can make sweet and fatty foods so tempting.

Research has linked sleep deprivatio­n and an increase in the production of neurotrans­mitters known as endocannab­inoids, which can lead to an increased feeling of hunger.

Another answer arises from an intriguing study by Northweste­rn University researcher­s that found the sense of smell goes a bit haywire in people not getting adequate sleep. A sharp increase in sensitivit­y to scents was followed by muddled brain messaging related to energy needs.

The researcher­s suspect this could lead to a craving for energy-dense foods.

No wonder we reach for the takeout menu and the snack drawer when we’ve missed out on sleep.

While the occasional comfort food cheat is fine, you’ll feel better with healthier fare. Plan ahead with meals that include highqualit­y protein and complex carbs, which will help you feel full and satisfied.

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 ?? STOCK.ADOBE.COM ?? Craving junk food is not uncommon when you’re sleep-deprived.
STOCK.ADOBE.COM Craving junk food is not uncommon when you’re sleep-deprived.

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