Chicago Tribune (Sunday)

Monkeypox shots race spurs fears of coronaviru­s failings

- By Maria Cheng

LONDON — Moves by rich countries to buy large quantities of monkeypox vaccine, while declining to share doses with Africa, could leave millions of people unprotecte­d against a more dangerous version of the disease and risk continued spillovers of the virus into humans, public health officials are warning.

Critics fear a repeat of the catastroph­ic inequity problems seen during the coronaviru­s pandemic.

“The mistakes we saw during the COVID-19 pandemic are already being repeated,” said Dr. Boghuma Kabisen Titanji, an assistant professor of medicine at Emory University.

While rich countries have ordered millions of vaccines to stop monkeypox within their borders, none have announced plans to share doses with Africa, where a more lethal form of monkeypox is spreading than in the West.

To date, there have been more than 22,000 monkeypox cases reported in nearly 80 countries since May, with about 75 suspected deaths in Africa, mostly in Nigeria and Congo.

On Friday, Brazil and Spain reported deaths linked to monkeypox, the first reported outside Africa. Spain reported a second monkeypox death Saturday.

“The African countries dealing with monkeypox outbreaks for decades have been relegated to a footnote in conversati­ons about the global response,” Titanji said.

Scientists say that unlike campaigns to stop COVID19, mass vaccinatio­ns against monkeypox won’t be necessary. They think targeted use of the available doses, along with other measures, could shut down the expanding epidemics that were recently designated

by the World Health Organizati­on as a global health emergency.

Yet while monkeypox is much harder to spread than COVID-19, experts warn if the disease spills over into general population­s — currently in Europe and North America it is circulatin­g almost exclusivel­y among gay and bisexual men — the need for vaccines could intensify, especially if the virus becomes entrenched in new regions.

On Thursday, the Africa Centers for Disease Control and Prevention called for the continent to be prioritize­d for vaccines, saying it was again being left behind.

“If we’re not safe, the rest of the world is not safe,” said Africa CDC’s acting director, Ahmed Ogwell.

Although monkeypox has been endemic in parts of Africa for decades, it mostly jumps into people from infected wild animals and has not typically spread very far beyond the continent.

WHO is developing a vaccine-sharing mechanism for affected countries, but has released few details about how it might work. The U.N. health agency has made no guarantees about prioritizi­ng poor countries in Africa, saying only that vaccines would be dispensed based on epidemiolo­gical

need.

Some experts worry the mechanism could duplicate the problems seen with COVAX, created by WHO and partners in 2020 to try to ensure poorer countries would get COVID-19 shots. That missed repeated targets to share vaccines with poorer nations.

“Just asking countries to share is not going to be enough,” said Sharmila Shetty, a vaccines adviser for Doctors Without Borders. “The longer monkeypox circulates, the greater chances it could get into new animal reservoirs or spread to” the human general population, she said.

At the moment, there’s only one producer of the most advanced monkeypox vaccine: the Danish company Bavarian Nordic. Its production capacity this year is about 30 million doses, with about 16 million vaccines available now.

In May, Bavarian Nordic asked the U.S. to release more than 215,000 doses it was due to receive “to assist with internatio­nal requests the company was receiving,” and the U.S. complied, according to Bill Hall, a spokesman for the department of Health and Human Services.

The company declined to specify which countries it was allocating doses for.

 ?? LEA SUZUKI/SAN FRANCISCO CHRONICLE ?? While rich countries have ordered millions of monkeypox vaccines, none have yet announced plans to share doses with African countries.
LEA SUZUKI/SAN FRANCISCO CHRONICLE While rich countries have ordered millions of monkeypox vaccines, none have yet announced plans to share doses with African countries.

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