Connecticut Post

Problem with playing pharmacist

- Keith Roach, M.D. Readers may email questions to: ToYourGood­Health@med .cornell.edu or mail questions to 628 Virginia Dr., Orlando, FL 32803.

Dear Dr. Roach: My wife has been diagnosed with atrial fibrillati­on. Doctors tried an electrical cardiovers­ion, but it came back after a few days. She is taking metoprolol and Eliquis. We have read about the supplement­s red clover, turmeric, omega-3 and hawthorn. Should she discontinu­e the pharmaceut­icals and take supplement­s instead?

J.C.

Answer: Please don’t do that, and let me explain why.

Atrial fibrillati­on is an abnormal heart rhythm. The goal of treating it is first to relieve symptoms, such as fast heart rate and dizziness, and second, to reduce the risk of stroke. Blood clots can form inside the heart when the atria are fibrillati­ng (a chaotic, non-coordinate­d muscle movement). Those clots can break off and go into the blood vessels of the brain, causing cell death and loss of function in that part of the brain. That’s a stroke.

Your wife is taking metoprolol to slow the heart rate. Atrial fibrillati­on causes the ventricles to go too fast, causing a sensation of fast heart rate and palpitatio­ns. Metoprolol, a beta blocker, protects the heart from damage from a too-fast heart rate, in addition to relieving symptoms. Apixaban (Eliquis) is a powerful anticoagul­ant, reducing the risk of clot formation.

Red clover is usually used in herbal medicine for its estrogen-like activities. Unfortunat­ely, estrogens INCREASE clot risk, so this herbal medicine absolutely should not be used by someone at risk for clots. Sweet clover hay is the source of warfarin (Coumadin), another often-used anticoagul­ant in people with atrial fibrillati­on: This may be the source of confusion. However, warfarin needs to be dosed precisely, with frequent blood level checks.

Turmeric is an antioxidan­t that does have some mild anticoagul­ant properties. However, it is not remotely powerful enough to do the job of protecting your wife adequately from stroke.

Omega-3 fish oils were once thought to reduce risk of atrial fibrillati­on; unfortunat­ely, a 2013 study showed no benefit.

Hawthorn has two potential benefits: To a slight extent, it acts as a beta blocker (like metoprolol) as well as an anticoagul­ant. However, no trials have proven its effectiven­ess. It may interfere with both her medicines. The metoprolol and Eliquis have much more safety data.

Dr. Roach Writes: In a recent column, a reader noted she had a history of irritable bowel syndrome and described intermitte­nt sharp rectal pain. My answer discussed control of her IBS. When I saw the column printed in the newspaper, weeks after I wrote it, I realized instantly that the diagnosis was probably proctalgia fugax, which is a spasm of the muscles of the anus. It is thought to be related to nerve compressio­n. I learned from my predecesso­r of this column, Dr. Paul Donohue, that sitting on a baseball or tennis ball can sometimes stop the pain instantly, and that creams and sometimes oral or inhaled medication­s can be effective in harder-to-treat cases.

I also want to point out that I fell victim to something called an anchoring heuristic error. I read about my reader’s irritable bowel and became “anchored” to that diagnosis.

Admitting an error and trying to understand why it happened are critical to reducing the likelihood of making the same error again. Anyone can make a mistake; it’s important to learn from them.

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