Mahomes on target in Chiefs' rout
Patrick Mahomes threw for 360 yards and five touchdowns, lifting the Kansas City Chiefs to an impressive 44-21 road win over the Arizona Cardinals on Sunday.
Mahomes was playing his first NFL game against Kliff Kingsbury, who coached him in college at Texas Tech and now leads the Cardinals.
The 2018 MVP threw three touchdown passes on Kansas City's first three drives.
Tight end Travis Kelce caught eight passes for 121 yards and a touchdown. Clyde Edwards-Helaire hauled in two touchdown passes.
Mahomes completed 30 of 39 passes. SAINTS 27, FALCONS 26 >> Wil Lutz kicked a 51-yard field goal with 19 seconds remaining to cap a stunning fourth-quarter comeback by visiting New Orleans, which overcame a 16-point deficit to beat Atlanta in Saints coach Dennis Allen's debut.
After struggling offensively through most of the game, Jamies Winston guided the Saints to three straight scoring drives. The first two ended with touchdown passes of 3 and 9 yards to Michael Thomas. BROWNS 26, PANTHERS 24 >> Rookie Cade York kicked a go-ahead 58-yard field goal with 8 seconds left, Kareem Hunt scored two TDs and Cleveland spoiled Baker Mayfield's bid for vengeance by beating host Carolina.
Nick Chubb ran for 141 yards as the Browns won their season opener for the first time since 2004.
Mayfield overcame a slow start, leading the Panthers back from a 13-point fourth-quarter deficit by running for a 7-yard touchdown and finding Robbie Anderson for a 75yard touchdown strike. He then led the Panthers on a 64-yard drive in seven plays to set up Eddy Pineiro's go-ahead field goal with 1:13 left.
BUCCANEERS 19, COWBOYS 3 >> Tom Brady and Mike Evans connected on a punctuating touchdown, Leonard Fournette ran for 127 yards, and visiting Tampa Bay dominated Dallas, whose quarterback Dak Prescott departed in the fourth quarter after his right hand struck a defender when throwing a pass.
VIKINGS 23, PACKERS 7 >> Minnesota's Justin Jefferson smashed visiting Green Bay for 184 receiving yards and two touchdowns, giving new coach Kevin O'Connell his first win.
Aaron Rodgers' first game without Davante Adams was a struggle. Rodgers went 22 for 34 for 195 yards.
RAVENS 24, JETS 9 >> Lamar Jackson threw three touchdown passes, including two to Devin Duvernay, and Baltimore rolled past host New York.
GIANTS 21, TITANS 20 >> Daniel Jones hit Chris Myarick for a 1-yard touchdown pass, then found Saquon Barkley on a shovel pass for the 2-point conversion with 1:06 left against host Tennessee, making New York's Brian Daboll a winner in his coaching debut.
The Titans had a chance to win as time expired. But Randy Bullock pushed a 47-yard field goal wide left.
COMMANDERS 28, JAGUARS 22 >> Carson Wentz bounced back from throwing interceptions on consecutive plays early in the fourth, completing his third and fourth touchdowns to give Washington a comeback victory at home against Jacksonville.
Wentz was 27 of 41 for 313 yards.
EAGLES 38, LIONS 35 >> Jalen Hurts accounted for 333 yards and a touchdown and A.J. Brown had 155 yards receiving in his Philadelphia debut against host Detroit.
The Eagles scored 24 points in the second quarter and had a 17-point lead in the fourth that was cut to three when Jared Goff threw a 22yard touchdown pass to DJ Chark with 3:51 left.
DOLPHINS 20, PATRIOTS 7 >> Tua Tagovailoa passed for 270 yards and a touchdown and Miami beat Bill Belichick and visiting New England.
Tyreek Hill, making his Dolphins debut after the team traded for him during the offseason, had eight receptions for 94 yards.
COLTS 20, TEXANS 20, OT >> Matt Ryan rallied Indianapolis in the fourth quarter to force overtime at Houston in his Colts debut, but neither team could score on two overtime possessions each.
The Texans led 20-3 entering the fourth quarter in coach Lovie Smith's debut, but Ryan led three successive scoring drives, culminating with his 15-yard touchdown pass to Michael Pittman with 1:54 remaining.