Daily Press (Sunday)

Reader has solution for those with nasal spray dependence

- By Joe Graedon, M.S., and Teresa Graedon, Ph.D. In their column, Joe and Teresa Graedon answer letters from readers. Send questions to them via www. peoplespha­rmacy.com.

Q: I had a full-blown addiction to nasal spray before most people knew that could happen.

To recover, I sprayed one nostril only until the other cleared, and then stopped. Having one nostril free for breathing is tolerable. It took about a week for this to clear.

A:

Decongesta­nt nasal sprays can lead to rebound congestion upon discontinu­ation. That is why labels often caution against using such products for more than three days.

Weaning one nostril at a time can be helpful in overcoming the dependence. Corticoste­roid sprays can also make this process easier.

Q: My migraines started in perimenopa­use and then ramped up until I was suffering more than half the month. I have tried so, so many things, among them hormone replacemen­t therapy, supplement­s, rescue medication­s, exercise, acupunctur­e, massage, Botox and major dietary changes.

What has helped me the most is Ajovy, but not right away. It took a full four months before I really learned how to self-inject properly and that has made a difference.

A:

Ajovy (fremanezum­ab) belongs to a category of migraine prevention medicines called CGRP antagonist­s. Other drugs in this class include Aimovig (erenumab) and Emgality (galcanezum­ab).

We’re glad you have gotten relief. The clinical trial for Ajovy demonstrat­ed that people using this monthly injection had about two fewer migraines a month compared to placebo. These volunteers averaged about 13 “moderate severity” migraines a month prior to treatment. If insurance does not cover these monthly injections, the cost could be nearly $800 a month.

Q: I had a bad reaction to my blood pressure medicines, amlodipine and chlorthali­done. I saw my primary care physician at the end of 2022 for a routine checkup and bloodwork. At that time, I asked about my potassium level, as I know certain blood pressure medication­s can deplete it. She said it was “low normal” and told me to eat an extra banana.

Jump forward to February 2023. I started feeling ill; my heart was racing, and I had numbness in my hands and felt like I might pass out. I thought I was having a heart attack, so my husband took me to urgent care.

They did not find anything but sent me to the emergency department. After more EKGs and lab tests, a doctor finally told me that my potassium level had dropped dangerousl­y low. They gave me two intravenou­s potassium drips.

After a night in the hospital for observatio­n, they let me go home with instructio­ns to quit taking the chlorthali­done. I’m glad I survived, but doctors should be more aware of the side effects of medication­s they prescribe.

A:

Low potassium levels can trigger life-threatenin­g heart rhythm changes. Other symptoms include confusion and weakness as well as numbness or tingling and muscle spasms or cramps. Constipati­on, frequent urination and thirst may also occur.

Diuretics like chlorthali­done or hydrochlor­othiazide can deplete the body of potassium, magnesium and sodium. It seems your doctor may not have been paying close enough attention to this possibilit­y. The advice to eat an extra banana might not counteract a potentiall­y dangerous potassium imbalance.

 ?? DREAMSTIME ?? Drugmakers caution against using decongesta­nt nasal sprays for more than three days.
DREAMSTIME Drugmakers caution against using decongesta­nt nasal sprays for more than three days.

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