Daily Times (Primos, PA)

Widener prof receives grant to ‘advance science of neonatal care’

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CHESTER » Anita Singh, Ph.D., assistant professor of biomedical engineerin­g at the Widener University School of Engineerin­g, has received the National Science Foundation’s Faculty Early Career Developmen­t (CAREER) Award. This multi-year research grant of $549,214 is one of the foundation’s most prestigiou­s awards that will allow her to continue her innovative research on the prevention of neonatal brachial plexus palsy (NPBB), a birth-related injury that can cause loss of movement or weakness of the arm. Through her research, Singh aims to develop possible preventati­ve and treatment strategies that can advance the science of neonatal care.

“Receiving the CAREER grant is a great accomplish­ment for both me and my school,” said Singh. “This funding offers dual benefits: it will support our research to develop a tool to address and solve an ongoing clinical issue, as well as create firsthand learning opportunit­ies for our students to work on funded research projects with very high clinical impact.”

A rising leader in NPBB prevention and treatment research, Singh joined the Widener faculty in 2014. This is the third federal grant awarded to Singh for her teaching and research since her arrival at the university, and second awarded in relation to her work on NPBB prevention and treatment. In 2017, she received a multi-year academic research enhancemen­t award (AREA) grant for more than $415,000 from the U.S. Department of Health and Human Services through the Eunice Kennedy Shriver National Institute of Child Health & Human Developmen­t. That funding has allowed her to study biomechani­cal and physiologi­cal injury thresholds and the resulting structural changes of the neonatal brachial plexus.

The CAREER grant builds on Singh’s NIHfunded research to investigat­e NBPP injury outcomes that occur specifical­ly during hypoxia, a medical condition that is often caused by complicate­d deliveries that result in low oxygen in a newborn’s tissues. Singh and her research team hypothesiz­e that babies born under hypoxic conditions are more vulnerable to injury and therefore predispose­d to NBPP.

Over the next five years, Singh and her team, comprised of both undergradu­ate and graduate students from Widener, will collect experiment­al data that will be used in computer-based models that serve as a tool used to develop strategies for prevention of birth-related injuries including NBBP. Their highly translatio­nal work should enhance obstetrici­ans’ care and training. Given the clinical relevance of this research, Singh will lead a multi-collaborat­ive team including clinicians and engineers from Drexel University, Shriners Children’s Hospital and Wayne State University, where Singh earned her Ph.D.

“This grant is a major achievemen­t for the School of Engineerin­g and Dr. Singh, and it speaks volumes about our faculty’s commitment to not only leading innovative, funded research, but providing students with opportunit­ies to participat­e in it with them,” said Widener President Julie E. Wollman. “The funding will create hands-on learning experience­s for our students that will help prepare them for successful careers.”

Funding for the research comes from the National Science Foundation Faculty Early Career Developmen­t Award (1752513). The National Science Foundation’s CAREER Program is a foundation-wide activity that offers support of earlycaree­r faculty who have the potential to serve as academic role models in research and education and to lead advances in the mission of their department or organizati­on.

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