Dayton Daily News

World’s first in vitro cheetah cubs born at Columbus Zoo

- By Alissa Widman Neese

The first cheetah cubs ever conceived through in vitro fertilizat­ion have entered the world, marking a breakthrou­gh for zoo breeding programs — a feat achieved in central Ohio, at the Columbus Zoo and Aquarium.

The zoo announced the birth early Monday. The pair of cubs, a male and a female, born Wednesday night to 3-year-old, first-time mother, Isabelle, or “Izzy,” are healthy and bonding together in a den located in a behind-the-scenes area of the zoo, according to a statement.

The zoo continues to monitor them with a remote camera.

“These two cubs may be tiny, but they represent a huge accomplish­ment, with expert biologists and zoologists working together to create this scientific marvel,” said Dr. Randy Junge, the Columbus Zoo’s vice president of animal health. “This achievemen­t expands scientific knowledge of cheetah reproducti­on, and may become an important part of the species’ population management in the future.”

The zoo, with partners, decided to use the technique to expand the gene pool of cheetahs in human care. The cubs are not Isabelle’s biological offspring, but instead were conceived using eggs and sperm from other cheetahs with more valuable DNA.

A biologist from the Smithsonia­n Conservati­on Biology Institute in Front Royal, Virginia, which leads wildlife research projects worldwide, fertilized the eggs outside the womb in a laboratory and incubated them before implanting the embryos into both Isabelle and her sister, 3-year-old Ophelia, in November.

In December, an ultrasound confirmed Isabelle was pregnant. Ophelia did not become pregnant.

A cheetah’s pregnancy typically lasts about three months. They’re known for being the fastest animals on land, capable of running 65 mph to 75 mph in short bursts.

The Columbus Zoo is a member of the Associatio­n of Zoos and Aquariums, a nonprofit group of more than 230 accredited institutio­ns in the U.S. and abroad. Associatio­n members use a planning process called Species Survival Plans to guide its breeding programs, meticulous­ly tracking the genetic history of their animals and recommendi­ng the best breeding pairs.

 ?? COLUMBUS ZOO AND AQUARIUM ?? One of two cheetah cubs born last Wednesday at the Columbus Zoo and Aquarium yawns in their den. The litter was the first in the world to be conceived using in vitro fertilizat­ion, a crucial effort to improve genetic diversity and support the species’ survival.
COLUMBUS ZOO AND AQUARIUM One of two cheetah cubs born last Wednesday at the Columbus Zoo and Aquarium yawns in their den. The litter was the first in the world to be conceived using in vitro fertilizat­ion, a crucial effort to improve genetic diversity and support the species’ survival.

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