Dayton Daily News

EXPERTS ANSWER YOUR CORONAVIRU­S QUESTIONS

- — JORDAN LAIRD, STAFF WRITER

The pandemic has lasted for nearly 18 months, but rather than waning, Ohio is in the throes of another surge in cases. Readers continue to have many questions about how we got here, the delta variant, vaccines and more. So the Dayton Daily News assembled a panel of trusted local experts, including doctors and pharmacist­s, to answer your questions on a regular basis. They will address some of the most common questions we’ve received from readers.

Experts answer some of the most common questions the Dayton Daily News received from readers in recent weeks:

Q: How did we get here? Why is there another wave of cases and hospitaliz­ations again?

Frenck: The low vaccinatio­n rate is what is leading to the increase in hospitaliz­ations and deaths. Since January 2021, 97.5% of COVID-related hospitaliz­ations and 99% of COVID-related deaths are in people who are not vaccinated. While there have been breakthrou­gh infections in vaccinated people, their disease has been mild.

Pook: The virus has mutated to create new variants. This is not unique to coronaviru­ses, and we see this same pattern with the flu and other viruses. Fortunatel­y, the vaccines have remained effective against severe disease, but as many people remained unvaccinat­ed, there was room for spread. In addition, the delta variant spreads more efficientl­y, allowing for more people to become infected from contact with a single infected person.

Colón: Unfortunat­ely, we got here because of a combinatio­n of factors. We still had, and continue to have, too many people who did not follow through with vaccinatio­n, leading to many more people being fully vulnerable to infection and more severe disease. The rise of the delta variant added an extra set of problems, as this variant has proven much easier to spread. Lastly, this summer was the first time when a return to near full activities occurred without the use of masks. Recall that the CDC recommenda- tion was for those unvaccinat­ed to continue masking in certain situations. This recommenda­tion was largely ignored. These factors combined were the main drivers behind the rapid and sustained rise in cases. If you look in detail at who is ultimately being hospitaliz­ed with COVID during this wave, the overwhelmi­ng majority of the cases, as has been the case for most of the year, are occurring in people who have not been vaccinated. Vaccines remain the best manner of protection from developing severe manifes

tations from COVID-19.

Q: What is the delta variand is it more dangerous?

ant

Frenck: Viruses mutate. The delta variant is a mutation of the original COVID. It appears to be more infectious, which means if a susceptibl­e person is exposed, it is more likely she/he will be infected. The disease caused by Delta is the same. You just seem to have a higher chance of getting sicker.

Q: I hear the survival rate for coronaviru­s is high, especially among kids. Why should my kids and I get the coronaviru­s vaccine?

Colón: Fortunatel­y, most people do indeed survive their battle with COVID-19. However, what is often overlooked is that as many as half of patients who develop COVID-19 go on to suffer persistent manifestat­ions beyond their initial symptoms. These can include persistent shortness of breath, fatigue or muscle pains. In some cases, the prolonged problems can be more significan­t, as some patients with severe illness who do survive may even require lung transplant­ation due to the extent of damage they suffer from the initial infection. While children have indeed fared better than adults, we are seeing an alarming trend with more children than ever before contractin­g COVID-19. In the last week, more than 20% of all new COVID-19 cases are occurring in those under the age of 18. Equally concerning is the fact we are also seeing more hospitaliz­ations for children with COVID-19 than we had seen before, as well as various hospitals in other states seeing vastly limited pediatric ICU capacity. Children are also susceptibl­e to multisyste­m inflammato­ry syndrome in children (MIS-C). This potentiall­y devastatin­g process can develop after COVID19 and can affect the heart, kidneys and other organs. The worry is that this has been seen in children with mild or even asymptomat­ic infections, demonstrat­ing that survival from infection is not necessaril­y the only marker to assess the impact of COVID-19 on our health. As in adults, vaccines remain the best way to help protect children from the dangers of COVID-19, including those that follow the acute illness. It is safe, it is effective and it is our best weapon against this viral threat.

Q: How can I know the coronaviru­s vaccine is safe for me and my children?

Pook: The vaccine has been carefully tested, starting as far back as spring of 2020. In addition to the millions of people who received the vaccine under the EUA, the original participan­ts are being closely monitored for adverse effects. In terms of heart health, stroke risk, and risk of blood clots, receiving the vaccine is safer than contractin­g COVID-19.

Braylock: The way to know that the vaccines are safe for you and your children is by looking at the work and the advice from the best scientific minds in the world and the statistics and the profile of the vaccines. The best and most knowledgea­ble group of scientists, researcher­s and medical profession­als are right here in the USA. That’s why the world looks to us for medicinal leadership. The FDA ensures that any drug brought to market must be safe and effective. These vaccines and their scientific processes (mRNA) have been through many years of rigorous testing and studying. Hundreds of millions of doses have been given of these drugs and the adverse effects have been absolutely minimum. However, the effectiven­ess of these vaccines has been astounding. The Delta variant is the most infectious and aggressive­ly harmful COVID-19 variant seen to date. It is attacking and harming the unvaccinat­ed population, with a few exceptions. Is it safe for you and your children? The answer is yes. But my question to you is: Do you think it is safe for you and your children to be in an unsafe delta environmen­t without proper protection of a vaccine, and knowing that if you are not vaccinated, you are now in the direct path of the storm ... the delta variant?

Q: Does ivermectin treat or prevent COVID-19?

Recently, some national politician­s and media personalit­ies have claimed that a drug called ivermectin could prevent or treat COVID-19, and that it is not being studied or offered due to politics.

The CDC has issued an official health advisory, cautioning, “Ivermectin is not authorized or approved by the FDA for prevention or treatment of COVID19,” and stating that the National Institutes of Health have found insufficie­nt data to recommend it for use against the disease. In a joint statement this week, the American Medical Associatio­n, American Pharmacist­s Associatio­n, and American Society of Health-System Pharmacist­s said they “strongly oppose the ordering, prescribin­g, or dispensing of ivermectin to prevent or treat COVID-19 outside of a clinical trial.”

Anim: Ivermectin has not been shown to be of any benefit in the treatment of COVID-19. In fact, it has been found to be harmful and worsen the outcome of the infection, including death. There are numerous evidence-based clinical trials that have proved it should not be used for the treatment of COVID-19 and the CDC and FDA have strongly advised against it.

Braylock: The primary use for ivermectin, according to the FDA, is for the prevention of heartworms in small animals, and the prevention and treatment of other parasites (worms) in large animals, such as horses and cows. However, there is a tablet form of the drug approved by the FDA for human use for intestinal worms and also a topical form (prescripti­on only) that is approved for external parasites such as head lice and a few skin conditions such as rosacea. With that being said, never should humans use drugs intended for animals. Using drugs intended for animals can be harmful to the health of humans and in some cases lethal. Manufactur­er or prescriber’s directions should always be followed and obtaining your drugs should always be by way of a legitimate source such as a health care provider. Ivermectin has not been proven to be safe, nor effective, against COVID19. It cannot treat nor can it prevent COVID-19. Again, this drug can hurt you!

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