EQUUS

BAD BACTERIA, GOOD USE

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Botulin, the toxin produced by Clostridiu­m botulinum bacteria, is one of the deadliest known neurotoxin­s. But it does have some worthwhile medical applicatio­ns.

Perhaps the best-known use of botulinum toxin is in Botox injections that prevent wrinkles in people by relaxing the facial muscles. But Botox is also used therapeuti­cally to prevent migraines in people and it shows promise for treatment of some conditions in horses.

In a study from The Netherland­s, Botox injections reduced the severity of stringhalt, a neuromuscu­lar disorder that causes gait abnormalit­ies.

In addition, Botox may be injected into the deep digital flexor muscle of horses with laminitis to lessen the pull on the coffin bone. The goal is to prevent the separation of the weakened connective tissues between the bone and the hoof wall.

In all cases, the effects of Botox injection are temporary and wear off within about three months.

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