DE­TEC­TION AND DI­AG­NO­SIS

EQUUS - - Conversati­ons -

A num­ber of tests are cur­rently avail­able that make use of the an­ti­bodyanti­gen bond to de­ter­mine whether a horse has been ex­posed to S. neu­rona or N. hugh­esi, as well as how re­cently the in­fec­tion oc­curred. All have ad­van­tages and draw­backs.

The West­ern blot is an older method that is still in use. A pos­i­tive re­sult on a West­ern blot in­di­cates the pres­ence of an­ti­bod­ies to S. neu­rona, but it can­not dis­tin­guish an older in­fec­tion from a cur­rent, ac­tive one. The test may, how­ever, be able to rule out EPM in a horse who has no an­ti­bod­ies. (Cur­rently, there is no com­mer­cially avail­able West­ern blot test to de­ter­mine ex­po­sure to N. hugh­esi.)

Newer tests iden­tify the quan­tity as well as the type of an­ti­bod­ies present in the horse’s blood. Higher titers of the an­ti­bod­ies may in­di­cate a more

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