2. RE­DUCED IM­MU­NITY

EQUUS - - Longevity -

An in­evitable ef­fect of ag­ing is im­munose­nes­cence, the tech­ni­cal term for a de­cline in im­mune func­tion, which leads to greater vul­ner­a­bil­ity to ill­ness and in­fec­tion. “There is break­down in the ac­tual func­tion of im­mune cells,” says Adams. “One of the things re­search has shown is that there is re­duced T-cell func­tion---there are fewer T-cells to un­dergo pro­lif­er­a­tion.”

T-cells, or T-lym­pho­cytes, are a type of white blood cell in­te­gral to im­mune func­tion. When T-cells en­counter a for­eign pathogen for the first time, they mul­ti­ply rapidly and release large

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