68. DONNA KARAN
$475 million SOURCE: Fashion AGE: 72 • RESIDENCE: New York City SELF-MADE SCORE: 8
Karan sold her namesake fashion label to luxury-goods conglomerate LVMH for $195 million in 2000. Since then, she’s focused on her lifestyle brand, Urban Zen, which combines fashion, philanthropy and art. This year, Karan also cofounded Urban Zen Integrative Therapy, a company that will integrate Eastern self-care practices with Western medicine.