NET WORTH: $1.6 billion (ª from $5 billion)
Afeyan and his Moderna cofounder, Robert Langer, shot into The Forbes
400 last year, along with founding investor Timothy Springer, when shares of the biotech rm behind one of the two leading Covid-19 vaccines hit an all-time high in August 2021. As a CDC study showed its boosters’ eectiveness had worn o and cases of the virus slowed, shares fell 67%, enough to knock all three o this year’s list. Moderna’s chairman, Afeyan is tasked with overseeing its rebound eorts. No stranger to adversity, he and his parents £ed Lebanon in 1975 when civil war broke out.