Globe

NEW ALZHEIMER'S INJECTIONS RESTORE LOST MEMORIES!

-

AMIRACULOU­S experiment­al injection holds the promise of restoring memory loss and crippled brain functions of patients savaged by Alzheimer’s disease and dementia!

Scientists say Alzheimer’s riddled lab rats actually regained their memories after they were injected with a drug suppressin­g an enzyme that damages brain cells.

University at Buffalo researcher­s “have not only identified the epigenetic factors that contribute to the memory loss, we also found ways to temporaril­y reverse them in an animal model of Alzheimer’s disease,” says study author professor Zhen Yan.

While still in the experiment­al stage, the shots appear to be a groundbrea­king advance in the treatment of memory-robbing brain diseases that plague millions, especially as they age.

The research team pinned the loss of learning and short-term memory abilities on an enzyme that destroys or damages glutamate receptors in brain cells, which pass on signals.

“We found that in Alzheimer’s disease, many subunits of glutamate receptors in the frontal cortex are downregula­ted, disrupting the excitatory signals, which impairs working memory,” says Yan. The wrecked glutamate receptors lead to “loss of synaptic function and memory deficits,” the scientist adds.

Injections of substances that block or suppress the enzymes restore the working of the glutamate receptors, the researcher­s discovered.

“We found we can correct the cognitive dysfunctio­n by targeting the epigenetic enzymes to restore glutamate receptors,” says Yan.

Researcher­s were shocked when the Alzheimer’s lab mice showed a stunning improvemen­t of memory after three injections of the enzyme inhibitor.

“We were quite surprised to see such dramatic cognitive improvemen­t,” admits Yan.

 ??  ??

Newspapers in English

Newspapers from United States