Globe

WORLD’S FIRST PIG-TO-HUMAN KIDNEY SWAP!

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FOR the first time ever, a pig’s kidney was transplant­ed to a human and not immediatel­y rejected by the patient’s body, a blockbuste­r medical breakthrou­gh that may offer a lifeline to 100,000 Americans waiting for a new organ!

In a two-hour operation, surgeons at NYU Langone Health in New York City took an organ harvested from a geneticall­y engineered pig and attached it to a brain-dead woman, who’d previously displayed signs of kidney dysfunctio­n. The procedure was done with permission from the patient’s family before she was due to be removed from life support.

The modified pigs — dubbed GalSafe by their developer, Revivicor, do not carry the gene that produces alpha-gal, a sugar known to trigger an attack from the human immune system, leading to organ rejection.

Surgeons say the kidney was attached to the blood vessels in the woman’s thigh and kept outside the abdomen, where it was covered with a protective shield during the 54-hour study.

Team leader Dr. Robert Montgomery says test results showed the pig kidney’s function was comparable to that of a human donor.

“The kidney turned a beautiful pink color and immediatel­y urine started pouring out of the

ureter,” explains Montgomery.

While the FDA has approved the gene alteration process, the agency had not yet approved medical products derived from the pigs for use in humans, and so-called xenotransp­lants — from animals to humans — still face significan­t medical and regulatory reviews.

But Montgomery suggests the geneticall­y modified pigs “could potentiall­y be a sustainabl­e, renewable source of organs.”

 ?? ?? Transplant could save 100,000 in America alone
Transplant could save 100,000 in America alone
 ?? ?? The pigs lack the gene linked to an attack from the immune system
The pigs lack the gene linked to an attack from the immune system

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