Hartford Courant (Sunday)

Lifestyle changes can cut diabetes risk in half

- Howard LeWine, M.D., HARVARD HEALTH PUBLISHING THE MEDICINE CABINET

Q: On my last routine blood work¸ my blood sugar was just above the normal range. Am I destined to have diabetes?

A: Making small changes to your habits and daily lifestyle now can help prevent or at least delay the onset of Type 2 diabetes.

A large study published almost 20 years ago showed the strength of the connection between lifestyle habits and Type 2 diabetes risk.

The Diabetes Prevention Program (DPP) trial, which followed thousands of participan­ts in 27 areas across the country from 1996 to 2001, was the first major effort to look at whether lifestyle changes were more or less effective than drug interventi­on in preventing Type 2.

The study, published in 2002, included a diverse group of 3,234 Americans who had prediabete­s and were overweight. It found that those who lost a modest amount of weight ( just 5% to 7% of their starting weight) and increased their

physical activity by about 30 minutes a day reduced their risk of developing Type 2 diabetes by an impressive 58%. The diabetes drug

metformin also lowered risk, but less dramatical­ly — by 31%.

Since the original DPP trial, which lasted three years, there have been several follow-up studies with the original participan­ts. In these long-term studies, participan­ts have been asked to keep up the same lifestyle changes or metformin dose for over 20 years. The most recent 22-year follow-up study revealed that over 22 years, lifestyle changes reduced the developmen­t of Type 2 diabetes by 25%, while metformin reduced it by 18%.

Other studies have taken the original data from the DPP study and analyzed it to look for more connection­s. One analysis found that the

lifestyle changes in the DPP study had as much benefit for people at high genetic risk for Type

2 diabetes as those at lower genetic risk. Other studies in China, Finland, Europe, India and Canada have also found that lifestyle changes can delay Type 2 diabetes in people who are at risk. This suggests that even if Type 2 diabetes runs in your family, you can lower your risk of developing it by adopting some habits that help you be more active and lose a little weight.

Best of all? You don’t have to try to make these changes on your own. Perhaps the best thing to come out of the DPP study was a nation-wide program that provides support and encouragem­ent to people with prediabete­s wanting to make these changes. The interventi­on that was

used in the original DPP study was so successful that the CDC used it as a model to create the National Diabetes Prevention Program. You can find a CDC-certified lifestyle change program in your area by visiting the CDC website (cdc. gov/diabetes/prevention/index.html).

Those who lost a modest amount of weight (just 5% to 7% of their starting weight) and increased their physical activity by about 30 minutes a day reduced their risk of developing Type 2 diabetes by an impressive 58%.

 ?? ??

Newspapers in English

Newspapers from United States