Houston Chronicle Sunday

Exploring the vices that make us self-destruct

- By Sally Satel

What made acclaimed American writer David Foster Wallace doubt his talent so profoundly — and, ultimately, take his own life? Why would a university president make obscene phone calls to prospectiv­e baby sitters? How can we understand a beloved comic actor who relentless­ly consumes cocaine, endangerin­g himself, his family and his career?

In his ambitious new book, “Capture,” David A. Kessler — a former Food and Drug Administra­tion commission­er and a retired medical school dean at Yale and the University of California at San Francisco — tries to answer these questions. “What happens when our rational minds feel as though we’ve been hijacked by something we cannot control?” In other words, what happens when we are captured?

Kessler defines “capture” as a triad of basic elements. The first is a narrowing of attention. This is followed by a “perceived lack of control” and then a “change in emotional state.” What we end up doing, he writes, “may not be what we consciousl­y want.”

Kessler says he was drawn to study the power of unbidden influence — thoughts, feelings and behaviors that override reason and will — through his earlier FDA-related work on tobacco and obesity; he has written three books on those subjects. “Is it possible that the same biological mechanism that selectivel­y controls our attention and drives us to chain-smoke and overeat … is also responsibl­e for a range of emotional suffering?” he asks.

Kessler concludes that it is, and in a section on the neural underpinni­ngs of capture he explains the commonalit­ies. These include the basic workings of brain circuits that enable us to selectivel­y focus attention, couple sensory experience­s with feelings, form and recall memories, and learn. The result is behavioral patterns that are sometimes useful and sometimes destructiv­e.

But this is not a book about the brain. It is mostly devoted to narratives of figures, famous and unsung, who illustrate capture and self-destructio­n. In a chapter called “What Captures?,” Kessler identifies about 20 forms of undoing. In “Gambling,” he offers the 19th-century Russian novelist Fyodor Dostoyevsk­y, who wrote about and suffered from excessive gambling; in “Drink,” the late author Caroline Knapp explains her love affair with alcohol; under “Brutish Father,” there is Franz Kafka, whose demanding father greatly distressed him.

Kessler also shows that people who embrace the qualities of capture sometimes find salvation. This theme is explored through the lives of notable individual­s who fought their way back from depression, such as Winston Churchill and writer William Styron. Cartoonist Chris Ware, for example, was mired in self-loathing until he was transforme­d by the birth of a daughter. Spiritual revelation led Bill Wilson, known as Bill W., to co-found Alcoholics Anonymous. Thandi Shezi, a brutalized political prisoner in South Africa, found peace in forgivenes­s for her captors.

Kessler is an excellent storytelle­r, and “Capture” is bursting with human drama drawn from real lives rather than the bland, composite case studies that clinicians tend to favor. However, at the book’s core is a very slim thesis. Namely, that “our emotional struggles and mental illness” are driven by “a stimulus — a place, a thought, a memory, a person that takes hold of our attention and shifts our perception.”

Whether — and how — our perception shifts in response to stimuli we find meaningful is a function of personal history, temperamen­t and culture, as Kessler tells us. Sometimes this process is overt, other times unconsciou­s; typically it is a combinatio­n. But is this news? Short of gods, brain processes beyond our control (psychosis, compulsion­s, dementia, sensory distortion­s) or base survival instincts, what else drives human thought, feeling and action?

The author hopes that by understand­ing capture, we might “release those caught in its vicelike grip.” But the most he can do — the most anyone can — is point out that people can undergo reverse capture by forming strong attachment­s to new ideas, people and causes. Even so, this is not something one can do readily, in part because it’s extremely hard and in part because we don’t know in advance what kinds of commitment­s will come to be our salvation.

After a long career in public health, government and academic administra­tion, and the study of tobacco and overeating, the author seems to have been captured by literature and biography. And why not? These remain the best portals to insight into textured human experience. But the capture theory itself does not build meaningful­ly upon current knowledge, nor does it unravel any mystery of why, despite our best interests, we sometimes act as we do. Sally Satel is a psychiatri­st and resident scholar at the American Enterprise Institute. She is a co-author of “Brainwashe­d: The Seductive Appeal of Mindless Neuroscien­ce.”

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