Houston Chronicle Sunday

Study: Nev. man is first in U.S. infected twice

- By Jessica Schladebec­k NEW YORK DAILY NEWS

A Nevada man has become the first person in the United States to be diagnosed with coronaviru­s for a second time amid similar reports of reinfectio­n out of Hong Kong.

The 25-year-old from Reno initially tested positive for the virus in April. He later recovered but was again diagnosed in June — this time with significan­tly more severe symptoms, according to a new study from the University of Nevada Reno School of Medicine.

From there, he came down with pneumonia, which required hospitaliz­ation and oxygen treatment.

“Genetic tests from each episode showed that viruses were similar in major ways but differed in at least 12 spots that would be highly unlikely from natural evolution of the bug if the man had it continuous­ly rather than being infected a second time,” said Mark Pandori, director of the Nevada State Public Health Laboratory, in a statement.

One of his parents, with who he’d been living at the time, also became sickened with coronaviru­s in June. Doctors have speculated this is how the 25-year-old caught the virus a second time.

During his first bout with the illness, he had a sore throat, cough, headache, nausea and diarrhea, researcher­s wrote in a pre-print study published Thursday. On May 31, he sought care for fever, headache, dizziness, cough, nausea and diarrhea.

Experts said after recovering for the first time, the man twice tested negative for the virus before being diagnosed with it again 48 days later. An examinatio­n of the genetic material has prompted researcher­s to believe that each case had been separate and distinct, ultimately suggesting people can sickened by the virus on more than one occasion.

The study, which has not been peer-reviewed by a journal, comes after Hong Kong researcher­s said they found the first documented case of coronaviru­s reinfectio­n in a 33-year-old man.

“After one recovers from COVID-19, we still do not know how much immunity is built up, how long it may last, or how well antibodies play a role in protection against a reinfectio­n,” Pandori said in a news release Thursday.

“If reinfectio­n is possible on such a short timeline, there may be implicatio­ns for the efficacy of vaccines developed to fight the disease. It may also have implicatio­ns for herd immunity,” Pandori said. “It is important to note that this is a singular finding. It does not provide any informatio­n to us with regard to the generaliza­bility of this phenomenon.”

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