Houston Chronicle

As Gates Foundation leader, her target is health care

- By Celia W. Dugger |

On her second anniversar­y as chief executive of the Bill & Melinda Gates Foundation, a global colossus of philanthro­py, Dr. Susan Desmond-Hellmann wrote of progress against smoking in the Philippine­s, polio across the world and sleeping sickness in Africa.

Before joining the foundation, she led developmen­t of the cancer drugs Avastin and Herceptin at Genentech, then was chancellor of the University of California, San Francisco.

We spoke for an hour at her office in Seattle. A condensed and edited version of the conversati­on follows.

Q: What are some of the coolest, most surprising things the foundation is doing?

A: What I think the foundation ought to be known for is making sure we do things that others can’t or won’t. So I wrote about the tobacco work for a couple reasons. One, people probably didn’t know we did tobacco-control work. I’m an oncologist, so I know that tobacco is the cause of death for 6 million people.

Q: What did you do in the Philippine­s?

A: They increased the tobacco tax. So we can pay, and did pay, for a group that can supply them with legal aid. If you’re a relatively small government and Big Tobacco, you might call it, has a legal staff that can challenge your use of a tax or a policy, you could access excellent legal advice.

Q: Tell us a little bit about how you’re trying to figure out what’s killing millions of kids before their fifth birthday.

A: If you look at what’s happened 1990 to 2015, vast improvemen­t. But we want to decrease by half again that under-5 mortality by 2030. About 40 percent of those deaths now are in the first 30 days of life, most coming actually on your birthday. So here’s a good news story. We know where pregnant women have HIV in sub-Saharan Africa, so we can do extremely effective, nearly universall­y effective ARVs (antiretrov­irals) for pregnant women. Using that precision public health, we decreased HIV transmissi­on from mother to child in sub-Saharan Africa by nearly half in five years. So we’re doing surveillan­ce.

Q: You’re doing actual autopsies?

A: What we’re doing actually is minimally invasive tissue sampling. So the way that we used to do it — and we still do it — is actually reasonably effective but excruciati­ngly difficult. A baby dies and you go to Mom, and it might be weeks after the death, and you say, “Did the baby have a fever, were they holding their stomach, did they vomit?” A verbal autopsy, it’s called. What we’re doing is adding minimally invasive tissue sampling: liver, lung.

Q: How will you use the informatio­n?

A: Most importantl­y, we can start to see here’s what we believe about epidemiolo­gy of HIV, TB (tuberculos­is), malaria, all of the things that we think are going on, and here’s actually truth. I want the Minister of Health to say here’s why babies die in this community, in my country. What do I have in my tool kit? What are the kinds of medicines I want my government to buy?

Q: Bill Gates and the foundation have joined the fight against polio. Do you think this is going to be the year that it ends?

A: It’s almost like you’re afraid to celebrate, but Nigeria has been polio-free now for over a year, and that means the continent of Africa has been wild polio virus-free for over a year. And we’re down to Pakistan and Afghanista­n. I’m a believer. I think we’re at the end of polio.

Q: You’ve been managing the foundation for two years now, and you’ve been managing Bill and Melinda Gates. What have you learned about their styles, their passions?

A: I would say that the two of them have three things in common: They’re fierce. They’re so all in. They’re generous. And they’re really committed to their family. It’s a family foundation, and I’m a big family person. I’m one of seven kids, my husband’s one of seven kids. So I’ve had the opportunit­y to see them as parents and the Gates as a family. Bill Sr. works here. That’s kind of fun, too, and it’s so big a part of the history of this place.

Q: So it hasn’t complicate­d your life.

A: Oh, of course it’s complicate­d my life.

Q: How?

A: Bill and Melinda are my bosses. And like when I was accountabl­e to the president of the University of California or the CEO of Genentech, I always like to understand how do I work with my boss. Melinda’s really instinctiv­e. Melinda connects with the human condition.

Q: And what about Bill?

A: Bill is more the numbers guy. I go on trips with Bill and Melinda separately. The trip I took with Bill, we’re driving through Tanzania, and he misses nothing. He’s got the population of Tanzania, GDP of Tanzania, what proportion of their population is educated. He’s looking at every sign.

Q: You’re answering to both of them.

A: I’m answering to both of them, and what I’ve tried to do is to tap into each of their — they call them in their letter — their superpower­s. They have very different superpower­s, and yet what unifies them is this commitment to equity and generosity.

 ?? Ruth Fremson / The New York Times ?? Dr. Susan Desmond-Hellman has been at the helm of the Gates Foundation for two years.
Ruth Fremson / The New York Times Dr. Susan Desmond-Hellman has been at the helm of the Gates Foundation for two years.

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