Houston Chronicle

WINDOW IN THE DRAPES

- By Abdul-Kareem Ahmed, M.D.

“Our patient has surgery today, would you like to observe?” my doctoring mentor asked. Of course, I responded eagerly. Our patient was a 65-year-old woman who had suffered from epilepsy since childhood. Her frequent seizures caused two types of spells. She would repeat words in an endless loop, or she would experience drop attacks, when she would lose all muscle tone and fall.

For some patients, medication­s alone cannot free them from seizures. Among them, occasional­ly, an underlying structural abnormalit­y in the brain can be the nidus for electrical disarray. One such abnormalit­y is known as mesial temporal sclerosis, in which the inner part of the temporal lobe, a section of the brain that sits above the ear on both sides and mediates emotions and memory, becomes scarred.

This was our patient’s diagnosis. Today, she was scheduled to have her scarred brain tissue removed, a “temporal lobectomy.”

My mentor brought me to the surgery wing, where she introduced me to the attending neurosurge­on.

“This is Abdul-Kareem, he’s a first-year, and he’s interested in neurosurge­ry,” she said.

“Let’s see if we can cure him of that,” he quipped.

In the preoperati­ve area, our patient was waiting anxiously. I introduced myself to her and asked her permission to observe. She graciously agreed.

I grabbed a hat and mask and headed to the operating room, where a small army of people was busy setting up. It was my first surgery, ever, and I was nervous. Soon after, the patient was wheeled in on a gurney.

The anesthesio­logist went to work intubating her. Controllin­g what looked like a Dr. Seuss contraptio­n, delivering gases and medication­s by crank and lever, he deftly lulled her into a reversible coma.

The neurosurge­ry team, including the attending and his chief resident, started their ritual. They turned her head to the right to expose her left temple. The resident shaved her left scalp, then brushed away the cut hair. Some patients request a full shave. Others want a minimalist cut, perhaps to comb over what happened. Our patient wanted the latter. They cleaned her skin with iodine and draped her from head to toe. The 65-year-old grandmothe­r harrowed by epilepsy became a square patch of skin, a window for the surgeons.

The resident cut a large Cshape into her scalp, drawing blood. Slowly, she worked her way through to the bone, the cranium, cauterizin­g vessels here, scraping away tissue there, eventually turning a flap of her scalp open. Using a torque-sensing drill, she bored two separate holes into the cranium. She connected these holes with a finer drill to complete her craniotomy, removing a circle of bone and revealing the pearly white dura encasing the brain.

With the finest scissors, she cut this protective sheath and uncovered the temporal lobe of the brain.

My eyes opened wide. A cardinal sin in the operating room is to touch anything sterile, so I glued myself to the wall. But seeing the live human brain for the first time, I was drawn in. The brain pulsates, recoiling from pressure the heart generates with every beat. It was pristine, pure, perfect.

Over the next two hours, the resident and attending stayed focused on carving out the anterior temporal lobe, including the amygdala and hippocampu­s, structures that work in concert to mediate and encode emotions and memory. Using electrosur­gery forceps, they dissected this tissue away from the surroundin­g brain, purposeful­ly from every side. It was quiet work.

For decades, this specialize­d tissue, this part of the temporal lobe the size of a baby carrot had helped our patient feel love and fear, had let her recognize her siblings, children and grandchild­ren, had solidified moments worth rememberin­g. It had always resided there, tucked safely inside.

With one final maneuver, the tissue came loose. The resident placed this sliver neatly onto a sterile metal tray.

My first thought was that a horrific accident had occurred. Of course, removing this part of her brain was the point; it was the root of the epilepsy. Still, it seemed harsh. In “Do No Harm: Stories of Life, Death, and Brain Surgery,” Dr. Henry Marsh was poetic and succinct when he described surgery as “controlled and altruistic violence.”

The attending and the resident started piecing the patient together again. They closed her dura delicately. With thin metal plates, the resident reconstruc­ted her cranium, returning the bone that she had previously removed. Gradually, she closed the layers of her scalp, until a line of stitches was the only footprint left.

Sir Victor Horsley, one of the fathers of neurosurge­ry, conducted the first modern surgery for epilepsy in 1886, at the National Hospital for Paralysed and Epileptic in London. His patient was a young man who had suffered a skull fracture and developed epilepsy after being run over by a cab in Edinburgh. Horsley removed the scar that had formed in the man’s brain and relieved him of seizures. Our patient’s epilepsy arose from damage to a different part of the brain, but the idea was the same: safely remove the troublesom­e tissue.

Despite how invasive it seemed, temporal lobectomy for epilepsy caused by such scarring is the optimal treatment for select patients who have failed medical management. Some patients experience difficulty with language after surgery, but seizures are stopped in most. Unfortunat­ely, far too few with this condition get this surgery because of a lack of referral from their doctors.

Though some of this patient’s temporal lobe was removed on the left, she still had her memory and emotion structures intact on the right side of her brain, and she would be able to lead a normal life.

Six years later, the patient is free of seizures.

After years of lying unperturbe­d, the most hidden corners of our bodies are exposed and manipulate­d by surgeons, then put back together, all during a morning or afternoon. Like archaeolog­ists, surgeons explore, examine and explant, but they must leave minimal trace of their workings.

Surgery is unnatural. Surgery may appear harsh to the untrained eye, as it did to me then. Perhaps because of this, detachment is necessary. The patch, the window in the drapes, is not just for sterile technique.

 ?? Beatrice de Gea / New York Times ?? The hidden corners of our bodies are exposed and manipulate­d by surgeons, then put back together.
Beatrice de Gea / New York Times The hidden corners of our bodies are exposed and manipulate­d by surgeons, then put back together.

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