Houston Chronicle

Biden sets May for full supply of vaccine

Earlier target date for all shots comes amid J&J-Merck partnershi­p

- By Zeke Miller, Linda A. Johnson and Jonathan Lemire

WASHINGTON — President Joe Biden said Tuesday the U.S. expects to take delivery of enough coronaviru­s vaccine for all adults by the end of May — two months earlier than anticipate­d — and he pushed states to get at least one shot into the arms of teachers by the end of May to hasten school reopenings.

Biden also announced that drugmaker Merck will help produce rival Johnson & Johnson’s newly approved one-shot vaccine, likening the partnershi­p between the two drug companies to the spirit of national cooperatio­n during World War II.

“We’re now on track to have enough vaccine supply for every adult in America by the end of May,” Biden said.

Despite the stepped-up pace of vaccine production, the work of inoculatin­g Americans could extend well into the summer, officials said, depending both on the government’s capacity to deliver doses and Americans’ willingnes­s to roll up their sleeves.

Biden’s announceme­nts quickly raised expectatio­ns for when the nation could safely emerge from the pandemic with the promise of speedier vaccinatio­ns, but even as he expressed optimism, Biden quickly tempered the outlook for a return to life as it was before the virus hit.

“I’ve been cautioned not to give an answer to that because we don’t

know for sure,” Biden said, before saying his hope for a return to normal was sometime before “this time next year.”

As Biden spoke, states across the country were moving to relax virus-related restrictio­ns. This despite the objections of the White House and the nation’s top infectious disease expert, Dr. Anthony Fauci, who have warned against any relaxation of virus protocols until more Americans are vaccinated.

In Texas, GOP Gov. Greg Abbott moved to lift his state’s mask-wearing mandate and a host of other limitation­s. Michigan’s Democratic Gov. Gretchen Whitmer eased capacity limits on restaurant­s and both public and residentia­l gatherings.

Fauci has previously said the nation must achieve a vaccinatio­n rate of about 80 percent to reach “herd immunity.” Only about 8 percent of the population has been fully vaccinated, according to the Centers for Disease Control and Prevention, though the pace of vaccinatio­n has been increasing. The U.S. set a new daily record for injections last Thursday and Friday.

In hopes of increasing vaccinatio­ns even further. the Biden administra­tion told governors to make preparatio­ns to administer even more doses in the coming weeks. More shots are also headed toward the federally backed program to administer doses in retail pharmacies, which federal officials believe can double or triple their pace of vaccinatio­n.

More than 800,000 doses of the J&J vaccine will also be distribute­d this week to pharmacies, on top of the 2.4 million they are now getting from Pfizer and Moderna.

Those pharmacies will be key in getting the vaccines into the arms of teachers — particular­ly in the roughly 20 states where they have not been prioritize­d for shots. The aim is to help reopen schools to better educate students who have been at risk of falling behind during the pandemic and reduce the burden on parents who have had to choose between childcare and a job.

“Let’s treat in-person learning as the essential service that it is,” Biden said. Teachers will be able to sign up directly through participat­ing retail pharmacies, the administra­tion said.

White House press secretary Jen Psaki also announced Tuesday that the federal government was increasing supply of the Moderna and Pfizer vaccines to states next week to 15.2 million doses per week, up from 14.5 million previously. States will also receive 2.8 million doses of the J&J shot this week.

On a call with governors Tuesday, White House coronaviru­s coordinato­r Jeff Zients said states should prepare to administer 16 million to 17 million total weekly doses of Pfizer and Moderna vaccines by the end of March, climbing to 17 million to 18 million weekly by early April. The supply of J&J doses to states, expected to dip after the initial shipment this week, will climb to 4 million to 6 million weekly doses by the end of March and 5 million to 6 million doses weekly through the end of April.

Officials have said J&J faced unexpected production issues with its vaccine and produced only 3.9 million doses before being cleared for emergency use authorizat­ion on Saturday. The company has promised to deliver 100 million doses by the end of June.

Before the approval of the J&J shot, Biden had suggested that it would take until the end of July to have enough vaccine for every adult in the U.S.

Facing questions about the company’s slipping delivery schedule, J&J Vice President Richard Nettles told lawmakers on Capitol Hill last week that the company had faced “significan­t challenges” because of its “highly complex” manufactur­ing process.

The White House said Merck would devote two plants to the production process. One would make the vaccine and the other would handle inserting the vaccine into vials and ensuring strict quality controls.

When it was first announced that a COVID-19 vaccine was authorized for emergency use by the Federal Drug Administra­tion in the United States, the scientific community was finally able to exhale. As a Black physician and member of the scientific community, I was particular­ly encouraged because of the disproport­ionately higher rates of hospitaliz­ations and deaths from COVID-19 among the Hispanic, Black and Indigenous American population­s.

My relief, however, was short-lived. We continue to see troubling inequities with new reports showing that many people from the minority community are among the lowest currently receiving the new vaccines, and the highest to be hesitant about its safety and effectiven­ess. According to Pew Research Center, just 42 percent of Black adults are inclined to get vaccinated, compared to 63 percent of white adults and 83 percent of adult Asian Americans.

The hesitation to get vaccinated is certainly understand­able. Minorities have for centuries experience­d egregious experiment­ation without consent. Examples include J. Marion Sims, who used enslaved Black women as test subjects, to the federally sponsored, the secretive Tuskegee study where treatment for syphilis was intentiona­lly withheld, and the more recent unconsente­d use of tissue and cells taken from Henrietta Lacks while a cancer patient, Black America’s relationsh­ip to science and research has been in multiple instances exploitati­ve and inhumane.

But this vaccine is not another Tuskegee. Looking at the preliminar­y data on who is getting vaccinated tells us that. News reports to date indicate that those who are majority persons and wealthy, including some from outside of the U.S., are quite active in pursuing vaccinatio­ns in America. National results show that Black people were inoculated at levels far below their share of the population. At the end of January, composite data shows that less than 5 percent of the vaccinatio­ns had been administer­ed to Black people.

There is no doubt that the lack of equity in access is also playing a role in such low vaccinatio­n numbers. Currently, Black residents are significan­tly more likely than whites to live more than a mile from the closest vaccinatio­n facility. Online portals and phone applicatio­ns have been popular tools deployed across states to schedule vaccinatio­ns. But this leaves those who fall into “digital divides” and “app gaps” behind.

However, these challenges should not be compounded with fear. Some say that they want to wait and see if anything adverse happens to others who were vaccinated. This is a reasonable initial thought, but it should be weighed against the science, the demonstrat­ed use and the clear risks. The science, conducted in tens of thousands of people of multiple ethnicitie­s in multiple countries, shows a strong safety profile. Moreover, unlike the Tuskegee experiment­s, those advocating, conducting and overseeing the vaccinatio­n studies are among the first in line to take the COVID-19 vaccine themselves. In Tuskegee, known curative treatment was withheld from Black patients. Now the effort is to deliver preventati­ve vaccines. White Americans are getting these at disproport­ionate rates while underrepre­sented people are disproport­ionately bearing the brunt of the COVID-19 illnesses.

I chose to get the vaccine because I know and trust this science. At the same time, I recognize the logical concerns about the safety of the vaccine in a process that was indeed accelerate­d. While this vaccine was created unusually fast, the speed is the result of technologi­cal innovation­s that have actually been in developmen­t for two decades, supported by the National Institutes of Health and the Defense Advanced Research Projects Agency. In addition, there has been new federal economic support for more COVID-19 focused developmen­t and manufactur­ing processes in parallel. Now, as the country passes more than half a million dead, we have a means to stop this death toll.

Indeed, people of color have the most to lose in the fight against this virus, and therefore, the most to gain by getting vaccinated. Now we can take advantage of the very best that modern medical science has to offer. The weight of the evidence is overwhelmi­ngly clear for all people. Everyone eligible should get the vaccine when it is available for you to do so.

To improve equity in access to the vaccine, leaders in government and all sectors of industry must work to reach our most vulnerable groups where they are located. This is working now in the extremes of Alaska, which leads the nation in vaccinatio­n rates despite much of the Native population being in remote and isolated communitie­s. For underserve­d population­s nationally, this means direct communicat­ion, not phone apps. It means purposeful targeting and collaborat­ions with community churches, barber shops, Federally Qualified Health Centers and community health centers. It means vaccinatio­n hubs and providers placed in the underserve­d areas of Houston. It means equipping the most trusted figures in minority communitie­s with the best informatio­n to counter the myths. And it means closely monitoring vaccinatio­n assignment and delivery to ensure equitable inclusion. For minorities, this is indeed urgent.

Pettigrew is CEO of Engineerin­g Health and executive dean of Engineerin­g Medicine (EnMed) at Texas A&M University and Houston Methodist Hospital. He was the founding Director of the National Institute of Biomedical Imaging and Bioenginee­ring and is the latest recipient of the National Science Board’s Vannevar Bush Award.

 ?? Courtesy photo ?? Roderic Pettigrew says people of color have the most to lose in the fight against COVID-19 and therefore the most to gain by getting vaccinated.
Courtesy photo Roderic Pettigrew says people of color have the most to lose in the fight against COVID-19 and therefore the most to gain by getting vaccinated.

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